rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Natural products isolation
  name:
    name part: Cannell, Richard J. P.
    role:
      role term: editor.
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: nju
    place:
      place term: Totowa, N.J
    publisher: Humana Press
    date issued: �1998
    date issued: 1998
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (x, 473 pages) : illustrations.
  abstract: Natural Products Isolation provides a comprehensive introduction to techniques for the extraction and purification of natural products from all biological sources. The book opens with an introduction to separations and chromatography and discusses the approach to an isolation. Experienced experimentalists describe a wide array of methods for isolation of both known and unknown natural products, including initial extraction, open column chromatography, HPLC, countercurrent and planar chromatography, SFE, and crystallisation. Later chapters address specific issues in working with plants, marine organisms, water-soluble compounds, as well as scale-up, dereplication and follow-up of a natural product lead. For the less experienced, these chapters provide background information and hands-on advice - using real examples - about how to approach an extraction in general, when and how to apply a particular technique and how to modify conditions according to the nature of the compound being isolated. Geared to scientists with little experience of natural products extraction, but offering even skilled researchers valuable advice and insight, Natural Products Isolation lays the foundation for the potential extractor to isolate natural substances efficiently. Its methods and guidance will almost certainly play a major role in today's natural product discovery and development.
  table of contents: How to approach the isolation of a natural product / Richard J.P. Cannell -- Initial extraction and product capture / F. Patrick Gailliot -- Supercritical fluid methods / Ed Venkat and Srinivas Kothandaraman -- Isolation by low-pressure column chromatography / Gino M. Salituro and Claude Dufresne -- Isolation by ion-exchange methods / Claude Dufresne -- Isolation by preparative HPLC / Paul Stead -- Isolation by planar chromatography / Simon Gibbons and Alexander I. Gray -- Separation by high-speed countercurrent chromatography / James McAlpine -- Crystallization and final stages of purification / Norman Shankland, Alastair J. Florence, and Richard J.P. Cannell -- Dereplication and partial identification of natural products / Frank VanMiddlesworth and Richard J.P. Cannell -- Purification of water-soluble natural products / Yuzuru Shimizu -- Special problems with the extraction of plants / Gloria L. Silva, Ik-Soo Lee, A. Douglas Kinghorn -- Isolation of marine natural products / Amy E. Wright -- Scale-up of natural products isolation / Michael S. Verrall and Stephen R.C. Warr -- Follow-up of natural product isolation / Richard J.P. Cannell.
  note: edited by Richard J.P. Cannell.
  note: Includes bibliographical references and index.
  subject:
    topic: Natural products
  subject:
    topic: Extraction (Chemistry)
  subject:
    topic: SCIENCE
    topic: Chemistry
    topic: Organic
  subject:
    topic: Extraction (Chemistry)
  subject:
    topic: Natural products
  subject:
    topic: Biological Products
    topic: isolation & purification
  classification: QD415 .N355 1998
  classification: 547.7
  classification: QW 800
  related item:
    title info:
      title: Natural products isolation
    origin info:
      publisher: Totowa, N.J. : Humana Press, �1998
    identifier: (DLC) 98016651
    identifier: (OCoLC)38842129
  related item:
    title info:
      title: Methods in biotechnology ; 4
  identifier: 9781592592562
  identifier: 1592592562
  identifier: 0585246173
  identifier: 9780585246178
  identifier: 6610835993
  identifier: 9786610835997
  identifier: 0896033627
  identifier: 9780896033627
  identifier: 98016651
  identifier: http://search.ebscohost.com/login.aspx
  record info:
    record content source: N$T
    record creation date: 000808
    record change date: 20190114101349.0
    record identifier: ocm44956575
    language of cataloging:
      language term: eng