rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Dipeptidyl Aminopeptidases in Health and Disease
  name:
    name part: Back, Nathan.
    role:
      role term: editor.
  name:
    name part: Cohen, Irun R.
    role:
      role term: editor.
  name:
    name part: Kritchevsky, David.
    role:
      role term: editor.
  name:
    name part: Lajtha, Abel.
    role:
      role term: editor.
  name:
    name part: Paoletti, Rodolfo.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2003
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XXXII, 359 p. 72 illus. online resource.
  abstract: Proceedings of the International Conference on Dipeptidyl Aminopeptidases, held September 26-28, 2002, in Berlin, Germany. Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in this field have contributed to this book which presents a state-of-the-art view on these enzymes, at a time when our understanding of their function is growing ever more rapidly and therapeutic options become imminent. The sections of the book focus on various topics: - Structure and function of dipeptidyl aminopeptidases, - DPP IV-like proteins, - Immune mechanisms and immune disorders, - Cancer and angiogenesis, - Diabetes and metabolism, - Therapeutic implications.
  table of contents: Structure and Function of Dipeptidyl Aminopeptidases -- Dipeptidyl Peptidase IV Substrates -- Structure-Function Relationship of DPP IV: Insights into its Dimerisation and Gelatinase Activity -- Exploration of the Active Site of Dipeptidyl Peptidase IV From Porphyromonas gingivalis -- Modification of the Biological Activity of Chemokines by Dipeptidyl Peptidase IV — a Side Effect in the Use of Inhibitors? -- Molecular Chimeras and Mutational Analysis in the Prolyl Oligopeptidase Gene Family -- The Specificity of DP IV for Natural Substrates is Peptide Structure Determined -- New Results on the Conformations of Potent DP IV (CD26) Inhibitors bearing the N-terminal MWP Structural Motif -- Different Inhibition Mechanisms of Dipeptidyl Peptidase IV by Tryptophan Containing Peptides and Amides -- Re-Uptake Mechanisms of Peptide Fragments after DPP IV-Mediated Proteolysis in the Peripheral Nervous System -- DPP IV-Like Enzymes -- Dipeptidyl Peptidase IV Gene Family -- Seprase-DPPIV Association and Prolyl Peptidase and Gelatinase Activities of the Protease Complex -- Dipeptidyl Peptidase-IV Activity and/or Structure Homologues (DASH) in Transformed Neuroectodermal Cells -- Characterisation of Human DP IV Produced by a Pichia pastoris Expression System -- Isolation and Characterization of Attractin-2 -- Investigation of DP IV-dependent Protein-Protein Interactions using Surface Plasmon Resonance -- Immune Mechanisms and Immune Disorders -- Synergistic Action of DPIV and APN in the Regulation of T Cell Function -- CD26/DPP IV in Experimental and Clinical Organ Transplantation -- CD26 is Involved in the Regulation of T-Cell Plasma Membrane Compartmentation -- Inhibition of Dipeptidylpeptidase IV (DPP IV, CD26) Activity Modulates Surface Expression of CTLA-4 in Stress-Induced Abortions -- Dipeptidyl Peptidase IV/CD26 in T Cell Activation, Cytokine Secretion and Immunoglobulin Production -- Dipeptidyl Peptidase IV Inhibitors with the N-terminal MXP Sequence: Structure-Activity-…
  note: edited by Nathan Back, Irun R. Cohen, David Kritchevsky, Abel Lajtha, Rodolfo Paoletti.
  subject:
    topic: Medicine
  subject:
    topic: Pharmacy
  subject:
    topic: Immunology
  subject:
    topic: Internal medicine
  subject:
    topic: Biochemistry
  subject:
    topic: Biomedicine
  subject:
    topic: Immunology
  subject:
    topic: Pharmacy
  subject:
    topic: Internal Medicine
  subject:
    topic: Biochemistry, general
  classification: QR180-189.5
  classification: 616.079
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Experimental Medicine and Biology, 524
  identifier: 9780306479205
  identifier: http://dx.doi.org/10.1007/b105297
  record info:
    record creation date: 100301
    record change date: 20151030121110.0
    record identifier: 978-0-306-47920-5