rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Adrenomedullin in Cardiovascular Disease
  name:
    name part: Nishikimi, Toshio.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2005
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: X, 219 p. online resource.
  abstract: Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has a role in the pathogenesis of arteriosclerosis. Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease. Toshio Nishikimi, MD, PhD, is an Associate Professor in the Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.
  table of contents: Biochemistry of Adrenomedullin -- Adrenomedullin Receptor and Signal Transduction -- Adrenomedullin Gene -- Adrenomedullin Expression and Secretion -- Biological Action of Adrenomedullin -- Circulating Adrenomedullin -- Role of Adrenomedullin in Cardiovascular Diseases -- Adrenomedullin as an Adipokine -- Adrenomedullin Knockout Mouse and Transgenic Mouse -- Pleiotropic Effect of Adrenomedullin: Lessons from Pure Adrenomedullin Knockout Mouse -- Therapeutic Application of Adrenomedullin -- Therapeutic Potentials of Adrenomedullin for Heart Failure and Pulmonary Hypertension.
  note: edited by Toshio Nishikimi.
  subject:
    topic: Medicine
  subject:
    topic: Cardiology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Cardiology
  classification: RC681-688.2
  classification: 616.12
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Basic Science for the Cardiologist, 19
  identifier: 9780387254050
  identifier: http://dx.doi.org/10.1007/b107323
  record info:
    record creation date: 100301
    record change date: 20150519174115.0
    record identifier: 978-0-387-25405-0