Toll and Toll-Like Receptors: An Immunologic Perspective

• Main Author: Rich, Tina (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2005.
• Series: Molecular Biology Intelligence Unit
• Subjects: Life sciences.; Immunology.; Cell biology.; Life Sciences.; Cell Biology.

Toll Receptors and the Renaissance of Innate Immunity Elizabeth H. Bassett and Tina Rich Overview n the last few pages of Immunology: The Science of Self-Nonself Discrimination Jan Klein ponders on what he would study if he were to start over in the lab. ^ Dismissing the I antibody, MHC, the T-cell...

Table of Contents:

• The Function of Toll-Like Receptors
• Structures and Motifs Involved in Toll Signaling
• “Supramolecular” Activation Clusters in Innate Immunity
• Interleukin-1 Receptor/Toll-Like Receptor Signaling
• Virus Induced Signaling to Initiate the Interferon Mediated Anti-Viral Host Response
• The Induction of Dendritic Cell Activation and Maturation by Toll-Like Receptor Signaling
• Pathogen Avoidance Using Toll Signaling in C. elegans
• Forward Genetic Analysis of TLR Pathways
• Agonists of Toll-Like Receptor 9.