rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Cytochrome P450
    sub title: Structure, Mechanism, and Biochemistry
  name:
    name part: Ortiz de Montellano, Paul R.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2005
    edition: Third edition.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XX, 690 p. online resource.
  abstract: In this third edition of Cytochrome P450: Structure, Mechanism, and Biochemistry, Dr. Paul Ortiz de Montellano has brought together a group of new authors as well as authors from previous editions to produce a timely volume that will be of considerable interest to a broad array of P450 researchers. The explosion of discovery of CYP (cytochrome P450) genes through genome analysis—more than 3500 to date—provides the more than 10,000 scientists around the world who study these monooxygenases a rich source of interesting and important research problems. Many have remained central elements over the 18 years that span the three editions of this book, including mechanisms of catalysis, oxygen activation and inhibition, gene regulation, and P450 structure. Each new edition updates our knowledge of such central issues in the study of P450s, emphasizing the timeliness of this newest volume. In this newest edition, we find that the newest discussion of P450 structure includes information of bacterial (soluble) P450s interwoven with that of eukaryotic (membrane bound) of this superfamily, highlighting the newest developments in this area. The complete battery of human P450s is now known and summarized in the new edition. In addition, general overviews of plant P450s and those from microbes contained within this newest edition provide a broader view of P450 diversity than seen in earlier editions. Each of these three editions should be on bookshelves of laboratories studying P450s. The third edition of Cytochrome P450: Structure, Mechanism, and Biochemistry provides an opportunity to judge progress in many key areas of P450 research while at the same time learn of new directions in the field. It is an excellent and most useful volume. Dr. Michael R. Waterman, Ph.D., Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN The third edition of Cytochrome P450: Structure, Mechanism, and Biochemistry provides an exceptionally fine summary of our present k…
  table of contents: Models and Mechanisms of Cytochrome P450 Action -- Computational Approaches to Cytochrome P450 Function -- Structures of Cytochrome P450 Enzymes -- Electron Transfer Partners of Cytochrome P450 -- Activation of Molecular Oxygen by Cytochrome P450 -- Substrate Oxidation by Cytochrome P450 Enzymes -- Inhibition of Cytochrome P450 Enzymes -- Induction of Cytochrome P450 Enzymes -- Hormonal Regulation of Liver Cytochrome P450 Enzymes -- Human Cytochrome P450 Enzymes -- Cytochrome P450 and the Metabolism and Bioactivation of Arachidonic Acid and Eicosanoids -- Cytochrome P450s in Plants -- The Diversity and Importance of Microbial Cytochromes P450.
  note: edited by Paul R. Ortiz de Montellano.
  subject:
    topic: Pharmacy
  subject:
    topic: Pharmacology
  subject:
    topic: Biochemistry
  subject:
    topic: Pharmacy
  subject:
    topic: Pharmacy
  subject:
    topic: Biochemistry, general
  subject:
    topic: Pharmacology/Toxicology
  classification: RS1-441
  classification: 615.1
  related item:
    title info:
      title: Springer eBooks
  identifier: 9780387274478
  identifier: http://dx.doi.org/10.1007/b139087
  record info:
    record creation date: 100301
    record change date: 20151204150814.0
    record identifier: 978-0-387-27447-8