rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Mitochondria
    sub title: The Dynamic Organelle
  name:
    name part: Schaffer, Stephen W.
    role:
      role term: editor.
  name:
    name part: Suleiman, M-Saadeh.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2007
    edition: 1.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: X, 359 p. online resource.
  abstract: About the Series: Advances in Biochemistry in Heath and Disease presents state-of-the-art discussions in cutting-edge biochemical research, offering exciting developments that impact healthcare and disease research. Volumes in the series focus on cross-disciplinary biomedical research and examine various topics in biochemistry, cell biology, molecular biology, and biomedicine. Mitochondria: The Dynamic Organelle Mitochondria: The Dynamic Organelle focuses on the function of the mitochondria and the organelle’s role in cellular pathology. While the traditional function of the mitochondria is metabolic, recent cutting-edge studies have uncovered a central role for mitochondria in cell signaling, cell survival and cell death. Mitochondria: The Dynamic Organelle presents examples of crosstalk between the mitochondria and the rest of the cell, which serve a regulatory role by modulating the levels of key metabolites, ions and oxidants or the activities of key rate-controlling enzymes. Detailed descriptions of the involvement of membrane receptors, channels, enzymes and metabolites in the cardioprotective mechanisms of the mitochondria are provided. This volume also discusses the death pathways that are initiated by the mitochondria. Novel therapeutic interventions are proposed which interfere with the death cascades, thereby rescuing the cell from mitochondria-linked apoptosis and necrotic oncosis. Mitochondria: The Dynamic Organelle is a timely contribution that addresses the reemergence of the mitochondria as a key player in cellular function and pathology. Key topics: Amino acid metabolism Carbohydrate and lipid metabolism Citric acid cycle regulation and metabolite transport Electron transport and oxidative phosphorylation Ischemic preconditioning Mitochondrial apoptosis Mitochondrial DNA damage Mitochondrial permeability transition Mitochondrial ion transporters Necrotic oncosis and mitochondrial dysfunction Peroxisome proliferators-activated receptors (PPARs) Mitoc…
  table of contents: Mitochondrial Metabolism -- Regulation of Mitochondrial Respiration in Heart Muscle -- Regulation of Fatty Acid Oxidation of the Heart -- Regulation of Mitochondrial Fuel Handling by the Peroxisome Proliferator-Activated Receptors -- Molecular Structure of the Mitochondrial Citrate Transport Protein -- Regulation of Pyruvate and Amino Acid Metabolism -- Amino Acids and the Mitochondria -- The Dynamic Nature of the Mitochondria -- Mechanotransduction of Shear-stress at the Mitochondria -- Mitochondria as Initiators of Cell Signaling -- Formation of Reactive Oxygen Species in Mitochondria -- Mitochondrial Calcium: Role in the Normal and Ischaemic/Reperfused Myocardium -- Mitochondrial Ion Channels -- Mitochondria as Initiators of Cell Death -- The Mitochondrial Permeability Transition Pore – from Molecular Mechanism to Reperfusion Injury and Cardioprotection -- The Apoptotic Mitochondrial Pathway – Modulators, Interventions and Clinical Implications -- The Role of Mitochondria in Necrosis Following Myocardial Ischemia-Reperfusion -- Mitochondria as Modulators of Cell Death -- Mitochondria and Their Role in Ischemia/Reperfusion Injury -- Mitochondrial DNA Damage and Repair.
  note: edited by Stephen W. Schaffer, M-Saadeh Suleiman.
  subject:
    topic: Life sciences
  subject:
    topic: Molecular biology
  subject:
    topic: Biochemistry
  subject:
    topic: Cell biology
  subject:
    topic: Developmental biology
  subject:
    topic: Life Sciences
  subject:
    topic: Cell Biology
  subject:
    topic: Biochemistry, general
  subject:
    topic: Molecular Medicine
  subject:
    topic: Developmental Biology
  classification: QH573-671
  classification: 571.6
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Biochemistry in Health and Disease ; 2
  identifier: 9780387699455
  identifier: http://dx.doi.org/10.1007/978-0-387-69945-5
  record info:
    record creation date: 100403
    record change date: 20151204175301.0
    record identifier: 978-0-387-69945-5