rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Drug Addiction
    sub title: From Basic Research to Therapy
  name:
    name part: Rapaka, Rao S.
    role:
      role term: editor.
  name:
    name part: Sadée, Wolfgang.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2008
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XXIII, 782 p. 197 illus., 1 illus. in color. online resource.
  abstract: Drug Addiction: From Basic Research to Therapy provides a comprehensive overview of physiological, biochemical, genetic and behavioral pathways underlying drug addiction. Focusing on fundamental neurophysiological processes that overlap between drug addiction and other CNS disorders, this volume covers the translation of basic research into novel therapies, not only of drug addiction but a spectrum of related CNS disorders, including pain. Chapters are written by leading scientists with widely ranging expertise in synthetic and computational chemistry, molecular biology, genetics, neurosciences, drug discovery and development, drug targeting, and quantitative therapeutics, providing an unprecedented overview of a complex field of high societal signficance.
  table of contents: General Topics -- DARPP-32 Mediates the Actions of Multiple Drugs of Abuse -- Drug Discovery From Natural Sources -- Computational Methods in Drug Design: Modeling G Protein-Coupled Receptor Monomers, Dimers, and Oligomers -- Symbiotic Relationship of Pharmacogenetics and Drugs of Abuse -- Monoclonal Antibody Form and Function: Manufacturing the Right Antibodies for Treating Drug Abuse -- Cocaine- and Amphetamine-Regulated Transcript Peptides Play a Role in Drug Abuse and Are Potential Therapeutic Targets -- RNAi-Directed Inhibition of DC-SIGN by Dendritic Cells: Prospects for HIV-1 Therapy -- Viewing Chemokines as a Third Major System of Communication in the Brain -- Targeting the PDZ Domains of Molecular Scaffolds of Transmembrane Ion Channels -- Neuronal Nicotinic Acetylcholine Receptor Expression and Function on Nonneuronal Cells -- Transporters & Stimulants & Hallucinogens -- Role of Monoamine Transporters in Mediating Psychostimulant Effects -- Development of the Dopamine Transporter Selective RTI-336 as a Pharmacotherapy for Cocaine Abuse -- Serotonin Transporters: Implications for Antidepressant Drug Development -- Recent Advances for the Treatment of Cocaine Abuse: Central Nervous System Immunopharmacotherapy -- ? Opioids as Potential Treatments for Stimulant Dependence -- Regulation of Monoamine Transporters: Influence of Psychostimulants and Therapeutic Antidepressants -- Hallucinogen Actions on 5-HT Receptors Reveal Distinct Mechanisms of Activation and Signaling by G Protein-Coupled Receptors -- Recognition of Psychostimulants, Antidepressants, and Other Inhibitors of Synaptic Neurotransmitter Uptake by the Plasma Membrane Monoamine Transporters -- Dual Dopamine/Serotonin Releasers as Potential Medications for Stimulant and Alcohol Addictions -- Receptors of Mammalian Trace Amines -- Drug Design: Nicotine, Opioids and Related Ligands -- The Role of Crystallography in Drug Design -- Opioid Peptide-Derived Analgesics -- Opioid Ligands with Mixed ?/? Opioi…
  note: edited by Rao S. Rapaka, Wolfgang Sadée.
  subject:
    topic: Medicine
  subject:
    topic: Pharmacology
  subject:
    topic: Biomedicine
  subject:
    topic: Pharmacology/Toxicology
  classification: RM1-950
  classification: 615
  related item:
    title info:
      title: Springer eBooks
  identifier: 9780387766782
  identifier: http://dx.doi.org/10.1007/978-0-387-76678-2
  record info:
    record creation date: 100301
    record change date: 20151125201841.0
    record identifier: 978-0-387-76678-2