rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Ovarian Cancer
    sub title: Second Edition
  name:
    name part: Stack, M. Sharon.
    role:
      role term: editor.
  name:
    name part: Fishman, David A.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2010
    edition: 2.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVI, 408 p. 44 illus., 32 illus. in color. online resource.
  abstract: Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumor-specific therapeutics. Ovarian carcinogenesis, invasion, and metastatic dissemination require a complex cascade of interrelated genetic, molecular, and biochemical events that regulate the neoplastic transition of normal ovarian surface epithelium. This second edition includes exciting new advances in ovarian cancer detection and treatment and provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A more detailed understanding of these processes may ultimately translate into the development of novel approaches for the detection and control of ovarian cancer. "Ovarian Cancer prevention, detection and treatment remain a significant health care challenge. In this text thought leaders in the field address the critical biologic and clinical issues relevant to the disease. A comprehensive spectrum of topics is covered providing up to date information on scientific discoveries and management considerations." Steven T. Rosen, M.D.
  table of contents: Chemoprevention, Staging, and Novel Therapeutic Targets -- Chemoprevention of Ovarian Cancer -- Staging and Surgical Treatment -- Novel Therapeutic Targets -- Biomarker Targets and Novel Therapeutics -- Tumorigenesis and Biomarkers -- Tumor Suppressor Genes -- Epigenetics and Ovarian Cancer -- Aberrant Epithelial Differentiation in Ovarian Cancer -- The Human Kallikrein Gene Family: New Biomarkers for Ovarian Cancer -- Soluble Epidermal Growth Factor Receptor: A Biomarker of Epithelial Ovarian Cancer -- Activated Epidermal Growth Factor Receptor in Ovarian Cancer -- Tumor Progression, Metastasis, Research Models -- Ras-Superfamily GTP-ases in Ovarian Cancer -- Lipid Generation and Signaling in Ovarian Cancer -- Lysophosphatidic Acid and Invasion -- Cell Adhesion in Ovarian Cancer -- Microenvironmental Regulation of Ovarian Cancer Metastasis -- Organotypic Models of Metastasis: A Three-dimensional Culture Mimicking the Human Peritoneum and Omentum for the Study of the Early Steps of Ovarian Cancer Metastasis -- Animal Models of Ovarian Cancer.
  note: edited by M. Sharon Stack, David A. Fishman.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Human genetics
  subject:
    topic: Gynecology
  subject:
    topic: Oncology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Oncology
  subject:
    topic: Gynecology
  subject:
    topic: Cancer Research
  subject:
    topic: Human Genetics
  classification: RC254-282
  classification: 616.994
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Cancer Treatment and Research, 149
  identifier: 9780387980942
  identifier: http://dx.doi.org/10.1007/978-0-387-98094-2
  record info:
    record creation date: 100301
    record change date: 20151204152906.0
    record identifier: 978-0-387-98094-2