rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Application of Apoptosis to Cancer Treatment
  name:
    name part: Sluyser, Mels.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2005
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VIII, 370 p. online resource.
  abstract: Novel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suicide and to be removed from the body. Research is also directed to investigate why the cancer cells sometimes lose the ability to undergo apoptosis after a certain period of time and methods are being developed to reactivate this cell death process. This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer patients. Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER DRUGS. He brings together a collection of papers written by the world’s leading experts in these fields.
  table of contents: Disfunction of the Apoptotic Pathway in Cancer Cells -- Calcium Signaling and Apoptosis Resistance of Cancer Cells -- Cell Clearance and Cancer -- Specific, Pro-Poptotic Cell-Signaling: Design of Novel, Recombinant Targeted Antitumor Agents Operating Exclusively Through Modulation of Cellular Apoptotic Events -- Targeting Oncogenes Which Regulate Apoptosis -- Targeting Cyclins to Cause Cancer Cell Apoptosis -- Apoptosis Induction By Tumor- Targeted Toxins -- Targeting Cell-Death Pathways in Multiple Myeloma: Therapeutic Implications -- Cephalostatin 1-Induced Apoptosis in Tumor Cells -- Hamlet; A Novel Tool to Identify Apoptotic Pathways in Tumor Cells -- Cancer Immunotherapy: On the Trail of a Cure? -- Histone Deacetylase Inhibitors as a Treatment of Trail-Resistant Cancers -- Basis of Cell Kill Following Clinical Radiotherapy -- Imaging of Apoptotic Cells in vivo -- Apoptosis-Inducing Anticancer Drugs in Clinical Trials.
  note: by Mels Sluyser.
  subject:
    topic: Medicine
  subject:
    topic: Pharmacy
  subject:
    topic: Cancer research
  subject:
    topic: Molecular biology
  subject:
    topic: Pharmacology
  subject:
    topic: Life sciences
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  subject:
    topic: Biomedicine general
  subject:
    topic: Molecular Medicine
  subject:
    topic: Pharmacology/Toxicology
  subject:
    topic: Pharmacy
  subject:
    topic: Life Sciences, general
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781402033025
  identifier: http://dx.doi.org/10.1007/1-4020-3302-8
  record info:
    record creation date: 100301
    record change date: 20151204173525.0
    record identifier: 978-1-4020-3302-5