rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Brain Tumor Pathology: Current Diagnostic Hotspots and Pitfalls
  name:
    name part: Schiffer, Davide.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2006
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VI, 272 p. online resource.
  abstract: Since Bailey and Cushing (1926), all brain tumor classifications have been called histogenetic. The nosographic position that the tumor types progressively acquired in the classification systems derived from the resemblance of tumor cells to those of the cytogenesis, modified whenever new information became available from different biological research fields and especially from molecular genetics. Classically, on the basis of the rough correspondence between the mature/immature aspect of tumor cells and the benign/malignant biological behavior of the tumors, the histological labels contained a prognostic significance. The supposed origin of the tumors was thus a factor for prognosis. Later on, with the concept of anaplasia (Cox, 1933; Kernohan et al., 1949) new criteria were introduced for establishing the malignancy grades of tumors. Immunohistochemistry and later molecular genetics further refined the prognostic diagnoses, substantially increasing the opportunities to recognize the cell origin of tumors, beside revealing the pathogenetic mechanisms. Prognoses became more accurate, as required by the greater and more targeted possibilities of therapy.
  table of contents: The Origin of Gliomas in Relation to the Histological Diagnosis -- Molecular Genetics Outline of Brain Tumors -- General Remarks -- Astrocytic Tumors I -- Astrocytic Tumors II -- Oligodendroglial Tumors -- Ependymal Tumors -- Neuronal and Mixed Glio-Neural Tumors I -- Neuronal and Mixed Glio-Neural Tumors II -- Peculiar Tumors -- Cell Migration and Invasion -- Apoptosis -- The Ubiquitin-Proteasome System -- Angiogenesis -- Meningiomas.
  note: by Davide Schiffer.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Neurosciences
  subject:
    topic: Neurology
  subject:
    topic: Neurosurgery
  subject:
    topic: Pathology
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  subject:
    topic: Neurosciences
  subject:
    topic: Pathology
  subject:
    topic: Neurosurgery
  subject:
    topic: Neurology
  subject:
    topic: Biomedicine general
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781402039980
  identifier: http://dx.doi.org/10.1007/1-4020-3998-0
  record info:
    record creation date: 100301
    record change date: 20151204152250.0
    record identifier: 978-1-4020-3998-0