rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Mitochondrial Medicine
    sub title: Mitochondrial Metabolism, Diseases, Diagnosis and Therapy
  name:
    name part: Gvozdjáková, Anna.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2008
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XLV, 409 p. online resource.
  abstract: Mitochondrial Medicine is a relatively new area where several disciplines from basic science to clinical medicine converge. Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. A primary feature of mitochondrial dysfunction is impaired cellular bioenergetics. This book is based upon extensive data gathered over 30 years of clinical and experimental research. Internationally recognized authors share their experience and state-of-the-art knowledge in various fields of their expertise such as mitochondrial cardiology, neurology, diabetology, nephrology, immunology, rheumatology, reproductive medicine, sports medicine, and chronobiology, and guide readers through the disease process, from basic biochemical mechanisms to diagnosis to therapeutic aspects. Laboratory evaluation plays a very important role in the diagnosis of mitochondrial diseases, in addition to clinical assessment. This includes analysis of plasma/mitochondrial coenzyme Q10 content, mitochondrial respiratory chain function and oxidative phosphorylation in isolated mitochondria and biopsy material, and nuclear magnetic resonance methods. In addition to standard medical therapy to treat cardiac, CNS, and other involvements in the mitochondrial disease patients, adjunctive nutritional therapy is indicated primarily to improve mitochondrial function. Therapy include coenzyme Q10, a -lipoic acid, carnitine, w -3- and w -6-PUFA, vitamins and polarized light. Mitochondrial Medicine is dedicated to Dr. Frederick L. Crane, discoverer of Coenzyme Q10 in 1957, and to the Celebration of 50th year of Coenzyme Q10 discovery. This book is intended for general medical practitioners, for specialists such as cardiologists, neurologists, and diabetologists, biochemists, nutritionists, pharmacists, and also for graduate students.
  table of contents: Mitochondrial Physiology -- Oxidants, Antioxidants and Oxidative Stress -- Chronobiology, Chronomics and N-of-1 Tests of Timing Coenzyme Q10 -- Methods of Chronobiometric Analysis of Mitochondrial Function -- Mitochondrial Medicine -- Mitochondrial Cardiology -- Mitochondria of the Human Transplanted Heart -- Mitochondrial Diabetology -- Mitochondrial Nephrology -- Mitochondrial Bioenergetics of Skeletal Muscles -- Rheumatoid Arthritis -- Mitochondrial Immunology -- Mitochondrial “Spermatopathy” -- Methods for Diagnosis of Mitochondrial Diseases -- Nuclear Magnetic Resonance -- Clinical Aspects of Coenzyme Q10 in Relationship with Its Bioenergetic and Antioxidant Properties -- Coenzyme Q10 Supplementation in Clinical Medicine -- Coenzyme Q10 Supplementation in Experimental Medicine -- Omega-3-PUFA, Omega-6-PUFA and Mitochondria -- Carnitine -- Vitamins in Mitochondrial Function -- Polarized Light.
  note: edited by Anna Gvozdjáková.
  subject:
    topic: Pharmacy
  subject:
    topic: Medicine
  subject:
    topic: Human physiology
  subject:
    topic: Immunology
  subject:
    topic: Neurosciences
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Medicine/Public Health, general
  subject:
    topic: Pharmacy
  subject:
    topic: Human Physiology
  subject:
    topic: Immunology
  subject:
    topic: Neurosciences
  classification: R1
  classification: 610
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781402067143
  identifier: http://dx.doi.org/10.1007/978-1-4020-6714-3
  record info:
    record creation date: 100301
    record change date: 20151125191741.0
    record identifier: 978-1-4020-6714-3