rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Cancer Microenvironment and Therapeutic Implications
    sub title: Tumor Pathophysiology Mechanisms and Therapeutic Strategies
  name:
    name part: Baronzio, Gianfranco.
    role:
      role term: editor.
  name:
    name part: Fiorentini, Gianfranco.
    role:
      role term: editor.
  name:
    name part: Cogle, Christopher R.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2009
    edition: 1.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVI, 242 p. online resource.
  abstract: In the post-genomic era, cancer is a genetic disease. However, cancer genotype does not always equal cancer phenotype. Cancers with the same genetic abnormalities don’t always behave the same. Understanding and eradicating cancers will require an appreciation for cancer’s ecology. This book is the first to comprehensively explore and critically appraise cancer microenvironments and host interactions with an eye towards exploiting our understanding for new treatments. The team of contributors share amongst them impressive experiences at the laboratory bench and in the clinic. These physician-scientists have dedicated themselves to the tension between the urgency for cures and the technical challenges of discovery. The target audience includes clinical oncologists, clinical hematologists, research oncologists, research hematologists, immunologists, stem cell researchers, oncology and hematology fellows (trainees), oncology educators (graduate and undergraduate levels), and course book for graduate students and undergraduate students.
  table of contents: Tumor Physiopathology and Microenvironment Genesis -- Inflammation and Carcinogenesis: A Change in the Metabolic Process -- Tumor Microenvironment: Aspects of Stromal-Parenchymal Interaction -- Significance of Tumor Microenvironment on the Genesis of: Interstitial Fluid, Angiogenesis, Haemostatic/Haemorheologic Abnormalities. Pathogenesis and Therapeutic Aspects -- Cancer, Stem Cells and the Neoplastic Niche -- Tumor Microenvironment, Therapeutic Perspectives and Strategies for Normalization -- Barriers to Drug Delivery in Cancer: Clinical Implications -- Hypoxia, Hyperthermia, Chemotherapy: Interactions and Opportunities -- Effects of Molecularly Targeting Hypoxia in Oncology -- Significance of the Tumour Microenvironment in Radiotherapy -- Effects of Tumor Microenvironment on Immunity and Consequent Clinical Considerations -- Effects of Tumor Microenvironment on Hyperthermia, Photodynamic and Nanotherapy -- Targeting Tumour Vascularization from Bench to Bedside: Suggestions for Combination with Hyperthermia -- New Indications for Established Drugs Able to Modify Tumour-Host Interactions.
  note: edited by Gianfranco Baronzio, Gianfranco Fiorentini, Christopher R. Cogle.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Oncology
  subject:
    topic: Pathology
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  subject:
    topic: Oncology
  subject:
    topic: Pathology
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781402095764
  identifier: http://dx.doi.org/10.1007/978-1-4020-9576-4
  record info:
    record creation date: 100301
    record change date: 20151125192421.0
    record identifier: 978-1-4020-9576-4