rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: Rho GTPases in Cancer
  name:
    name part: Golen, Kenneth.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2010
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XXII, 206 p. online resource.
  abstract: The Rho GTPases in Cancer is the first volume to collect and summarize the current understanding of the Rho GTPases and their involvement in the progression of human cancer. The critical role of the Rho GTPases, their regulatory proteins, and their effectors in cancer progression has become increasingly evident over the past decade. As translational research increases on these proteins, their importance as keystone molecules in vital cellular process is highlighted. Thus, these molecules represent a major class of potential therapeutic targets that could be exploited clinically. This aspect of Rho GTPase biology is developing, therefore the contents of The Rho GTPases in Cancer should prove of interest to clinicians and members of the cancer research community wishing to develop new treatments for cancer.
  table of contents: An Overview of the Rho GTPases -- Overview of Rho GTPase History -- Rho Proteins in Cancer -- The Rho Regulatory Proteins in Cancer -- RhoGDIs in Cancer -- Signaling through Galpha12/13 and RGS-RhoGEFs -- Vav Proteins in Cancer -- Rho GTPase-Activating Proteins in Cancer -- The Rho GTPase Proteins and Cancer -- RhoBTB Proteins in Cancer -- RhoC GTPase in Cancer Progression and Metastasis -- RhoB GTPase and FTIs in Cancer -- Regulation of Rho GTPase Activity Through Phosphorylation Events: A Brief Overview -- The Rho-Regulated ROCK Kinases in Cancer.
  note: edited by Kenneth Golen.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Pharmacology
  subject:
    topic: Cell biology
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  subject:
    topic: Cell Biology
  subject:
    topic: Pharmacology/Toxicology
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781441911117
  identifier: http://dx.doi.org/10.1007/978-1-4419-1111-7
  record info:
    record creation date: 100301
    record change date: 20151125192517.0
    record identifier: 978-1-4419-1111-7