rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Drug Product Development for the Back of the Eye
  name:
    name part: Kompella, Uday B.
    role:
      role term: editor.
  name:
    name part: Edelhauser, Henry F.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2011
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 592 p. online resource.
  abstract: This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and implant dosage forms Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Clinical endpoints and regulatory path to drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Uday B. Kompella, Ph.D., Professor of Pharmaceutical Sciences & Ophthalmology, University of Colorado, developed functionalized nanoparticles, nanoporous microparticles, microparticles, injectable implants, dendrimers, liposomes, and in situ forming gels for the eye. He is a Fellow of the American Association of Pharmaceutical Scientists (2005) and the Association for Research in Vision and Ophthalmology (2010). He received Distinguished Scientist (2006) Award from the University of Nebraska. Henry F. Edelhauser, Ph.D., Professor of Ophthalmology, Emory University, made pioneering contributions towards transcorneal, transscleral, and suprachoroidal drug delivery to the eye. He is…
  table of contents: Selection of Drug Delivery Approaches for the Back of the Eye: Opportunities and Unmet Needs -- Microdialysis for Vitreal Pharmacokinetics -- Fluorophotometry for Pharmacokinetic Assessment -- Systemic Route for Retinal Drug Delivery: Role of the Blood-Retinal Barrier -- Topical Drug Delivery to the Back of the Eye -- Principles of Retinal Drug Delivery from Within the Vitreous -- Transscleral Drug Delivery -- Suprachoroidal and Intrascleral Drug Delivery -- Advances in Biodegradable Ocular Drug Delivery Systems -- Microparticles as Drug Delivery Systems for the Back of the Eye -- Nanotechnology and Nanoparticles -- Hydrogels for Ocular Posterior Segment Drug Delivery -- Refillable Devices for Therapy of Ophthalmic Diseases -- Targeted Drug Delivery to the Eye Enabled by Microneedles -- Ocular Iontophoresis -- Drug and Gene Therapy Mediated by Physical Methods -- Protein Drug Delivery and Formulation Development -- Drug Suspension Development for the Back of the Eye -- Regulatory Considerations in Product Development for Back of the Eye -- Clinical Endpoints for Back of the Eye Diseases -- Druggable Targets and Therapeutic Agents for Disorders of the Back of the Eye -- Development of Bile Acids as Anti-Apoptotic and Neuroprotective Agents in Treatment of Ocular Disease.
  note: edited by Uday B. Kompella, Henry F. Edelhauser.
  subject:
    topic: Medicine
  subject:
    topic: Pharmacology
  subject:
    topic: Pharmaceutical technology
  subject:
    topic: Ophthalmology
  subject:
    topic: Biomedicine
  subject:
    topic: Pharmacology/Toxicology
  subject:
    topic: Ophthalmology
  subject:
    topic: Pharmaceutical Sciences/Technology
  classification: RM1-950
  classification: 615
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: AAPS Advances in the Pharmaceutical Sciences Series, 2
  identifier: 9781441999207
  identifier: http://dx.doi.org/10.1007/978-1-4419-9920-7
  record info:
    record creation date: 110725
    record change date: 20151125231435.0
    record identifier: 978-1-4419-9920-7