rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Computational Neuroscience of Drug Addiction
  name:
    name part: Gutkin, Boris.
    role:
      role term: editor.
  name:
    name part: Ahmed, Serge H.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2012
    edition: 1.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIV, 342 p. online resource.
  abstract: Drug addiction is one of the most important public health problems in Western societies, and is a rising concern for developing nations. Over the past three decades, experimental research on the neurobiology and psychology of drug addiction has generated a tremendous amount of exciting data, from the molecular to the behavioral levels. As a result, a new and pressing challenge for addiction research is to formulate a synthetic theoretical framework that goes well beyond mere scientific eclecticism to deepen our understanding of drug addiction and to foster our capacity to prevent and to cure drug addiction. Recently, researchers from a broad spectrum of scientific disciplines – from pharmacokinetics to neuroeconomics – have begun to take up this challenge. Computational Neuroscience of Drug Addiction collects recent mathematical and neurocomputational modeling approaches to drug self-administration and addiction. This selection of chapters illustrates how mathematical modeling can contribute to our understanding of the mechanisms underlying the transition between the different stages of addiction, from initiation of regulated drug use and subsequent loss of control over drug use to relapse after long-term abstinence. The volume provides an overview of this emerging area and will serve as a standard reference for addiction researchers and quantitative scientists entering the field. .
  table of contents: Foreword: P Dayan -- Part 1 – Pharmacological-based models of addiction -- Chapter 1. Simple deterministic mathematical Model of maintained drug delf-Administration behavior and its pharmacological applications. V.L. Tsibulsky* and A.B. Norman -- Chapter 2. Intermittent Adaptation : A mathematical model of drug tolerance, dependence and addiction. A. Peper -- Chapter 3. Control theory and addictive behavior. D. Newlin, P.A. Regalia, T.I. Seidman, G. Bobashev -- Part 2 – Neurocomputational models of addiction -- Chapter 4. Circuit models of addiction: receptors and neural dynamics in nicotine self-administration. M. Graupner and B. Gutkin -- Chapter 5. N Dual-system learning models and drugs of abuse. N.D. Daw and D.A. Simon -- Chapter 6. Modeling decision-making systems in addiction. Z. Kurth-Nelson and A. D. Redish -- Chapter 7. Computational models of incentive-sensitization in addiction: Dynamic limbic transformation of learning into motivation. J. Zhang, K. C. Berridge, and J. W. Aldridge -- Chapter 8. Understanding addiction as a pathological state of multiple decision making processes: a neurocomputational perspective. M. Keramati, A. Dezfouli and P. Piray -- Part 3 – Economic-based models of addiction -- Chapter 9. Policies and priors. K Friston -- Chapter 10. Toward a Computationally Unified Behavioral-Economic Model of Addiction. E.T. Mueller, L.P. Carter and W.K. Bickel -- Chapter 11. Simulating Patterns of Heroin Addiction within the Social Context of a Local Heroin Market. L. Hoffer, G. Bobashev and R. J Morris.
  note: edited by Boris Gutkin, Serge H. Ahmed.
  subject:
    topic: Medicine
  subject:
    topic: Neurosciences
  subject:
    topic: Bioinformatics
  subject:
    topic: Computational biology
  subject:
    topic: Biomedicine
  subject:
    topic: Neurosciences
  subject:
    topic: Computer Appl. in Life Sciences
  classification: RC321-580
  classification: 612.8
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Springer Series in Computational Neuroscience ; 10
  identifier: 9781461407515
  identifier: http://dx.doi.org/10.1007/978-1-4614-0751-5
  record info:
    record creation date: 111026
    record change date: 20151030061029.0
    record identifier: 978-1-4614-0751-5