rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Crohn's Disease and Ulcerative Colitis
    sub title: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach
  name:
    name part: Baumgart, Daniel C.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVIII, 754 p. 151 illus., 116 illus. in color. online resource.
  abstract: The conditions of Crohn’s disease and ulcerative colitis are excellent examples of how the exponential growth of knowledge in biomedical science can make a remarkable impact on clinical practice and patient’s quality of life. It has led to the development of unique novel immunomodulatory treatments. These are continuously being refined to treat not only the two original conditions in the gut, but the systemic immunologic illness with its associated extraintestinal disorders. New therapies are sometimes complex and associated with important risks requiring a deeper understanding of their molecular principles from clinicians. Crohn’s Disease and Ulcerative Colitis serves as a unique combined resource for physicians and scientists addressing the needs of both groups. It will stimulate exchange and collaboration and shorten the path between discovery and application of new knowledge and also help clinicians understand new therapeutic concepts from their origins. This volume provides an introduction to mucosal immunology which forms the basis of modern immunotherapy. It also serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy as well as conventional and complex immunomodulatory principles. Each chapter is written by experts in their field and includes the most up to date information. Crohn’s Disease and Ulcerative Colitis will be of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis and related autoimmune disorders.
  table of contents: The genetics of inflammatory bowel disease -- Environmental factors in the epidemiology of inflammatory bowel disease.-The intestinal immune system in health -- Understanding the epithelial barrier in inflammatory bowel disease.- Intestinal microbiology and ecology in inflammatory bowel disease.- Microbial recognition and pathogen-associated molecular pattern (PAMP) receptors in inflammatory bowel disease -- Inflammasomes in inflammatory bowel disease.-Antimicrobial peptides in inflammatory bowel disease -- Vascular responses to intestinal inflammation in inflammatory bowel disease -- Immunobiology of dendritic cells in inflammatory bowel disease.-Immunobiology of T-Cells in inflammatory bowel disease -- Immunobiology of B-Cells in inflammatory bowel disease.-Immunobiology of monocytes and macrophages in inflammatory bowel disease -- Immunobiology of epithelial cells in inflammatory bowel disease -- The Th1, Th2 and Th17 paradigm in inflammatory bowel disease -- Preclinical studies using mouse models of inflammatory bowel disease.- Enhanced endoscopy in inflammatory bowel disease -- MRI in Inflammatory Bowel Disease -- CT in inflammatory bowel disease.-Ultrasound in inflammatory bowel disease.-Laboratory evaluation including novel diagnostic markers of inflammatory bowel disease -- Histology and pathology of inflammatory bowel disease -- Activity indices based assessment of disease activity in inflammatory bowel disease.- Endoscopic assessment of disease activity and mucosal healing in inflammatory bowel disease.-Evaluation of quality of life in inflammatory bowel disease -- The natural history of inflammatory bowel disease -- Conventional medical management of Crohn’s disease: sulfasalazine -- Conventional medical management of Crohn’s disease: corticosteroids.-Conventional medical management of Crohn’s disease: azathioprine and 6-mercaptopurine.- Conventional medical management of Crohn’s Disease: Methotrexate.-Biologic Treatment of Crohn’s Disease: Adalimumab -- …
  note: edited by Daniel C. Baumgart.
  subject:
    topic: Medicine
  subject:
    topic: Gastroenterology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Gastroenterology
  classification: RC799-869
  classification: 616.33
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781461409984
  identifier: http://dx.doi.org/10.1007/978-1-4614-0998-4
  record info:
    record creation date: 120201
    record change date: 20150519174802.0
    record identifier: 978-1-4614-0998-4