rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: NanoCellBiology of Secretion
    sub title: Imaging Its Cellular and Molecular Underpinnings
  name:
    name part: Jena, Bhanu P.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 70 p. 38 illus., 33 illus. in color. online resource.
  abstract: Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology. This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists.
  table of contents: Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology. This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists. Table of contetns: Introduction -- Materials & Methods -- Porosome Discovery -- Calcium & SNARE-Induced Membrane Fusion -- SNAREs need to reside in opposing membrane -- Membrane curvature dictates SNARE size -- Disassembly of membrane-associated SNARE complex -- CD spectroscopy confirm membrane requirement for t-/v-SNARE assembly -- SNAREs br ing opposing bilayers closer for calcium bridging -- Membrane lipids influence SNARE complex assembly-disassembly -- Vesicle swelling and content expulsion during cell secretion -- Secretory vesicle swelling is required for intravesicular content expulsion -- Molecular mechanism of secretory vesicle swelling -- Presence of beta receptors at the secretory vesicle membrane -- Conclusion and future studies.
  note: by Bhanu P. Jena.
  subject:
    topic: Life sciences
  subject:
    topic: Cell biology
  subject:
    topic: Microscopy
  subject:
    topic: Nanoscale science
  subject:
    topic: Nanoscience
  subject:
    topic: Nanostructures
  subject:
    topic: Life Sciences
  subject:
    topic: Biological Microscopy
  subject:
    topic: Nanoscale Science and Technology
  subject:
    topic: Cell Biology
  classification: QH201-278.5
  classification: 570.282
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: SpringerBriefs in Biological Imaging
  identifier: 9781461424383
  identifier: http://dx.doi.org/10.1007/978-1-4614-2438-3
  record info:
    record creation date: 120118
    record change date: 20151030011048.0
    record identifier: 978-1-4614-2438-3