rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Systems Biology of Parkinson's Disease
  name:
    name part: Wellstead, Peter.
    role:
      role term: editor.
  name:
    name part: Cloutier, Mathieu.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVI, 176 p. online resource.
  abstract: This text is the first to present a study of Parkinson’s disease from a Systems Biology perspective. By placing the condition at centre stage, the authors have been able to provide a wide ranging modelling and systems analysis that is focussed on a multi-facetted and highly complex condition. The book comprises a specially selected set of eight studies of important aspects of PD, covering all relevant scales of space and time. These are used to show how innovative sensing techniques, mathematical modelling, model analysis and computational simulation can throw new light on the dynamics of disease mechanisms that drive this important form of neurodegeneration.
  table of contents: Imaging of dopaminergic neurons and the implications for Parkinson’s disease -- Modelling and simulation of brain energy metabolism: energy and Parkinson's disease -- Systems Biology of Aging: Opportunities for Parkinson’s Disease -- Mitochondrion- and Endoplasmic Reticulum-Induced SK Channel Dysregulation as a Potential Origin of the Selective Neurodegeneration in Parkinson’s Disease -- Energetics of Ion Transport in Dopaminergic Substantia nigra Neurons: ion exchange dynamics at the pacemaking membrane -- Real-time In Vivo Sensing of Neurochemicals -- Modeling protein and oxidative metabolism in Parkinson's disease -- Mathematical Models of Dopamine Metabolism in Parkinson’s Disease -- Index.
  note: edited by Peter Wellstead, Mathieu Cloutier.
  subject:
    topic: Life sciences
  subject:
    topic: Neurosciences
  subject:
    topic: Systems biology
  subject:
    topic: Life Sciences
  subject:
    topic: Systems Biology
  subject:
    topic: Neurosciences
  subject:
    topic: Biomedicine general
  classification: QH301-705
  classification: 570
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781461434115
  identifier: http://dx.doi.org/10.1007/978-1-4614-3411-5
  record info:
    record creation date: 120507
    record change date: 20151125212339.0
    record identifier: 978-1-4614-3411-5