rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Emerging Concepts of Tumor Exosome–Mediated Cell-Cell Communication
  name:
    name part: Zhang, Huang-Ge.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VIII, 220 p. online resource.
  abstract: Tumor exsome-mediated cell-cell communication has grown increasingly important in cancer research. Recent findings on vesicle-based information transfer by exosomes have changed our view of the tumor microenvironment. Currently, exosomes represent the main extracellular processes implicated in the regulation of multiple physiological processes. Importantly, in cancer, exosomes contribute to the formation of the tumor microenvironment, promoting invasion, angiogenesis, immune regulation and metastasis. Therefore, exosomes could be considered one of the major forces acting locally or systemically to promote the continuous crosstalk between the tumor and its microenvironment, influencing the behavior of different cell types such as stromal, endothelial and bone marrow-derived cells. Given the ability of exosomes to export unneeded endogenous molecules from cells, these structures hold great potential as anticancer therapeutic agents. This volume gives a comprehensive review on current research in this area and also discuss future prospects as prognostic markers for cancer.
  table of contents: Preface -- The Cell Biology of Exosomes : Historical and Perspectives -- The role of exosomal shuttle RNA (esRNA) in cell-to-cell -- Exosomal lipids in cell-cell communication -- The Functional Importance Of Tetraspanins In Exosomes -- The effects of exosomes and related vesicles on cancer development, progression, and dissemination -- Circulating Cell-derived Vesicles Mediate Tumor Progression -- Immune modulation of T cells and natural killer cells by tumor-derived exosomes -- The Role Of Tumor Exosomes In Tumorigenicity -- Microenvironmental regulation of metastasis by exosomes -- Microvesicles and their Emerging Role in Cellular Therapies for Organ and Tissue Regeneration -- Index.
  note: edited by Huang-Ge Zhang.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Immunology
  subject:
    topic: Proteins
  subject:
    topic: Posttranslational modification
  subject:
    topic: Cell biology
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  subject:
    topic: Cell Biology
  subject:
    topic: Posttranslational Modification
  subject:
    topic: Protein Science
  subject:
    topic: Immunology
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781461436973
  identifier: http://dx.doi.org/10.1007/978-1-4614-3697-3
  record info:
    record creation date: 120905
    record change date: 20151103131926.0
    record identifier: 978-1-4614-3697-3