rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Systems Biology of Tuberculosis
  name:
    name part: McFadden, Johnjoe.
    role:
      role term: editor.
  name:
    name part: Beste, Dany J.V.
    role:
      role term: editor.
  name:
    name part: Kierzek, Andrzej M.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVI, 228 p. online resource.
  abstract: Tuberculosis remains one of the world’s biggest killers responsible for more than a million deaths each year. New drugs and new vaccines are urgently needed to tackle the disease. This book describes the application of this century’s first new science, systems biology, to the study of tuberculosis. After introducing the basic principles of systems biology, successive chapters describe how systems-based approaches provide new insights into gene regulation, metabolism, protein-protein interaction, host-pathogen interactions, the immune response, persistence, drug treatment and diagnosis of tuberculosis. This book will be an invaluable aid to anyone interested in exploring how the latest science is helping us to understand this ancient disease.
  table of contents: Foreword -- Modeling Mycobacterium tuberculosis H37Rv in silico -- Software Platform for Metabolic Network Reconstruction of Mycobacterium tuberculosis -- Probing Gene Regulatory Networks to Decipher Host-Pathogen Interactions -- Metabolism of Mycobacterium tuberculosis -- Protein-protein interaction in the –omics era: Understanding Mycobacterium tuberculosis function -- A systems biology approach for understanding granuloma formation and function in tuberculosis -- Stochastic gene expression in bacterial pathogens: a mechanism for persistence? -- Drug Discovery -- Diagnosis -- Index.
  note: edited by Johnjoe McFadden, Dany J.V. Beste, Andrzej M. Kierzek.
  subject:
    topic: Life sciences
  subject:
    topic: Medical microbiology
  subject:
    topic: Systems biology
  subject:
    topic: Microbiology
  subject:
    topic: Life Sciences
  subject:
    topic: Systems Biology
  subject:
    topic: Microbiology
  subject:
    topic: Medical Microbiology
  classification: QH301-705
  classification: 570
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781461449669
  identifier: http://dx.doi.org/10.1007/978-1-4614-4966-9
  record info:
    record creation date: 121206
    record change date: 20151125162145.0
    record identifier: 978-1-4614-4966-9