rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Systems Analysis of Human Multigene Disorders
  name:
    name part: Maltsev, Natalia.
    role:
      role term: editor.
  name:
    name part: Rzhetsky, Andrey.
    role:
      role term: editor.
  name:
    name part: Gilliam, T. Conrad.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2014
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIII, 122 p. 12 illus. in color. online resource.
  abstract: Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance.
  table of contents: Wellness and Health Omics Linked to the Environment: the WHOLE approach to personalized medicine -- Characterizing Multi-omic Data in Systems Biology -- High-throughput Translational Medicine: Challenges and Solutions -- Computational approaches for human disease gene prediction and ranking -- A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization -- Index.
  note: edited by Natalia Maltsev, Andrey Rzhetsky, T. Conrad Gilliam.
  subject:
    topic: Life sciences
  subject:
    topic: Human genetics
  subject:
    topic: Systems biology
  subject:
    topic: Life Sciences
  subject:
    topic: Systems Biology
  subject:
    topic: Human Genetics
  classification: QH301-705
  classification: 570
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Experimental Medicine and Biology, 799
  identifier: 9781461487784
  identifier: http://dx.doi.org/10.1007/978-1-4614-8778-4
  record info:
    record creation date: 131128
    record change date: 20151204144309.0
    record identifier: 978-1-4614-8778-4