rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Mathematical Oncology 2013
  name:
    name part: d'Onofrio, Alberto.
    role:
      role term: editor.
  name:
    name part: Gandolfi, Alberto.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2014
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: X, 334 p. 96 illus., 78 illus. in color. online resource.
  abstract: With chapters on free boundaries, constitutive equations, stochastic dynamics, nonlinear diffusion–consumption, structured populations, and applications of optimal control theory, this volume presents the most significant recent results in the field of mathematical oncology. It highlights the work of world-class research teams, and explores how different researchers approach the same problem in various ways. Tumors are complex entities that present numerous challenges to the mathematical modeler. First and foremost, they grow. Thus their spatial mean field description involves a free boundary problem. Second, their interiors should be modeled as nontrivial porous media using constitutive equations. Third, at the end of anti-cancer therapy, a small number of malignant cells remain, making the post-treatment dynamics inherently stochastic. Fourth, the growth parameters of macroscopic tumors are non-constant, as are the parameters of anti-tumor therapies. Changes in these parameters may induce phenomena that are mathematically equivalent to phase transitions. Fifth, tumor vascular growth is random and self-similar. Finally, the drugs used in chemotherapy diffuse and are taken up by the cells in nonlinear ways. Mathematical Oncology 2013 will appeal to graduate students and researchers in biomathematics, computational and theoretical biology, biophysics, and bioengineering.
  table of contents: Part I: Cancer Onset and Early Growth -- Modeling spatial effects in carcinogenesis: stochastic and deterministic reaction-diffusion -- Conservation law in cancer modeling -- Avascular tumor growth modeling: physical insight in skin cancer -- Part II: Tumor and Inter-Cellular Interactions -- A cell population model structured by cell age incorporating cell-cell adhesion -- A general framework for multiscale modeling of tumor–immune system interactions -- The power of the tumor microenvironment: a systemic approach for a systemic disease -- Part III: Anti-Tumor Therapies -- Modeling immune-mediated tumor growth and treatment -- Hybrid multiscale approach in cancer modelling and treatment prediction -- Deterministic mathematical modelling for cancer chronotherapeutics: cell population dynamics and treatment optimization -- Tumor Microenvironment and Anticancer Therapies: An Optimal Control Approach.
  note: edited by Alberto d'Onofrio, Alberto Gandolfi.
  subject:
    topic: Mathematics
  subject:
    topic: Cancer research
  subject:
    topic: Biomathematics
  subject:
    topic: Biophysics
  subject:
    topic: Biological physics
  subject:
    topic: Mathematics
  subject:
    topic: Physiological, Cellular and Medical Topics
  subject:
    topic: Cancer Research
  subject:
    topic: Biophysics and Biological Physics
  classification: QH323.5
  classification: 570.285
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Modeling and Simulation in Science, Engineering and Technology
  identifier: 9781493904587
  identifier: http://dx.doi.org/10.1007/978-1-4939-0458-7
  record info:
    record creation date: 141016
    record change date: 20151103130054.0
    record identifier: 978-1-4939-0458-7