rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Cancers in People with HIV and AIDS
    sub title: Progress and Challenges
  name:
    name part: Yarchoan, Robert.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2014
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVI, 389 p. 34 illus., 20 illus. in color. online resource.
  abstract: The association between AIDS and cancer was recognized from the beginning ofthe AIDS epidemic, when the appearance of Kaposi sarcoma in a cluster of youngmen was one of the first signs of this new disease. It was soon recognized that AIDSpatients are prone to develop a number of “AIDS-defining” cancers: Kaposi sarcoma,lymphoma, and cervical cancer. The development of effective combination anti-HIVtherapy starting around 1996 converted AIDS from a death sentence to a manageabledisease and led to dramatic shifts in the epidemic. As this therapy was able to improveimmune function in patients, the incidence of most “AIDS-defining” cancers decreased.There is a misconception, however, that AIDS has gone away. In fact, as AIDS patientsare living longer, the number of AIDS patients has more than doubled in the UnitedStates since 1996, and the AIDS population overall has increased in age. Also, as AIDSpatients are less likely to die of other complications, cancer is coming to the forefront as one of the most common causes of death in regions where AIDS drugs are widelyavailable.Moreover, the three “AIDS-defining” cancers are now taking a back seat toa number of other HIV-associated cancers, such as Hodgkin lymphoma, lung cancer,and anal cancer. In the developing world, AIDS-associated cancers are a major publichealth problem, and in some regions of sub-Saharan Africa, Kaposi sarcoma is themost common tumor in men. In recent years, there has been a vast increase in our understanding of HIV-associatedcancers. We now know, for example, that most are caused by other viruses and thatthe main role of HIV and immunodeficiency is to provide a supportive environmentfor the viruses to multiply and for the cancers to develop. But there remain a numberof unanswered questions and a need for improved prevention and therapy. In the 28chapters of this book, written by some of the most renowned experts in this field, wepresent up-to-date information on the cancers associated with HIV infecti…
  table of contents: HIV-associated Cancers: Overview -- Epidemiology of AIDS-defining Malignancies -- Epidemiology of non-AIDS Defining Malignancies -- HIV Cancers in Resource-limited Regions -- Kaposi's Sarcoma-associated Herpesvirus (KSHV) -- Epstein Barr Virus (EBV) -- Human Papillomavirus (HPV) -- Merkel Cell Polymavirus (MCV) -- Presentation and Pathogenesis of Kaposi's Sarcoma -- Management of Kaposi's Sarcoma -- Presentation and Pathogenesis of HIV Lymphomas -- Diffuse Large B-Cell Lymphoma -- Burkitt and Burkitt-Like Lymphoma -- Primary Effusion Lymphoma -- AIDS-related Central Nervous System Lymphoma -- Plasmablastic and Other Lymphomas -- Hodkin Lymphoma -- Multicentric Castelman Disease -- Cervical Cancer -- Anal Cancer -- Other HPV-Associated Cancers -- Lung Cancer in HIV Infection -- Hepattocellular Carcinoma in HIV-positive Patients -- Merkel Cell Carcinoma and Other HIV-associated Skin Cancers -- Conjuctival Carcinoma -- Malignancies in Children with HIV Infection -- cART and Supportive Care -- Stem Cell Transplantation.
  note: edited by Robert Yarchoan.
  subject:
    topic: Medicine
  subject:
    topic: Immunology
  subject:
    topic: Virology
  subject:
    topic: Infectious diseases
  subject:
    topic: Oncology
  subject:
    topic: Biomedicine
  subject:
    topic: Immunology
  subject:
    topic: Virology
  subject:
    topic: Infectious Diseases
  subject:
    topic: Oncology
  classification: QR180-189.5
  classification: 616.079
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781493908592
  identifier: http://dx.doi.org/10.1007/978-1-4939-0859-2
  record info:
    record creation date: 140709
    record change date: 20151204150343.0
    record identifier: 978-1-4939-0859-2