rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Neuroinflammation and Neurodegeneration
  name:
    name part: Peterson, Phillip K.
    role:
      role term: editor.
  name:
    name part: Toborek, Michal.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2014
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVII, 600 p. 48 illus., 35 illus. in color. online resource.
  abstract: State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases, and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer’s disease, Parkinson’s disease, stroke, viral encephalitis, and substance abuse. In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system. With rare exception, no or inadequate treatment exists for the diseases discussed in this book. An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.
  table of contents: The Blood Brain Barrier -- Immune Cell Trafficking in the Central Nervous System -- General Physiology and Pathophysiology of Microglia Inflammation and the Pathophysiology of Astrocytes in Neurodegenerative Diseases -- Oxidative stress, neuroinflammation, and neurodegeneration -- Peripheral Neuroimmune Interactions and Neuropathic Pain -- Innate and Adaptive Immune-Mediated Neuroinflammation and Neurodegeneration in Parkinson’s Disease -- Multiple sclerosis: impact on functioning of the blood-brain barrier -- Neuroinflammation in Alzheimer’s disease -- Neuroinflammation in Huntington’s Disease -- Neuroinflammation and immune regulation in ischemic stroke: identification of new pharmacological targets -- HIV/NeuroAIDS -- Herpes Simplex Virus Infections Of The Central Nervous System -- Congenital Cytomegalovirus Disease -- Japanese Encephalitis: A Tale of Inflammation and Degeneration in the Central Nervous System -- The biology and clinical consequence of infection with the human polyomavirus JCV -- Role of Retrovirus-Induced Transactivator Proteins in Neuroinflammatory Disease -- Immunopathogenesis of bacterial meningitis -- Cerebral Malaria -- HIV and Cocaine Interplay in HIV-associated Neurocognitive Disorders -- Methamphetamine Neurotoxicity and Neuroinflammatory Processes -- Drugs of Abuse and NeuroAIDS: Opiates -- Cannabinoids -- Alcohol and Neurodegeneration -- Cell-Based Drug Delivery for Improving Antiretroviral Therapeutic Outcomes -- Immunomodulatory Therapeutics for Neurodegenerative Diseases -- Therapeutic Potential Of Cannabinoids.
  note: edited by Phillip K. Peterson, Michal Toborek.
  subject:
    topic: Medicine
  subject:
    topic: Neurosciences
  subject:
    topic: Neurochemistry
  subject:
    topic: Neurobiology
  subject:
    topic: Biomedicine
  subject:
    topic: Neurosciences
  subject:
    topic: Neurochemistry
  subject:
    topic: Neurobiology
  classification: RC321-580
  classification: 612.8
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781493910717
  identifier: http://dx.doi.org/10.1007/978-1-4939-1071-7
  record info:
    record creation date: 140708
    record change date: 20150519190613.0
    record identifier: 978-1-4939-1071-7