rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Subunit Vaccine Delivery
  name:
    name part: Foged, Camilla.
    role:
      role term: editor.
  name:
    name part: Rades, Thomas.
    role:
      role term: editor.
  name:
    name part: Perrie, Yvonne.
    role:
      role term: editor.
  name:
    name part: Hook, Sarah.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2015
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIV, 431 p. 65 illus., 48 illus. in color. online resource.
  abstract: This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines. Twenty-one chapters are divided into four main parts: (I) Background; (2) Delivery Systems for Subunit Vaccines; (3) Delivery Routes, Devices and Dosage Forms; and (4) Pharmaceutical Analysis and Quality Control of Vaccines. Part one provide a basic background with respect to immunology and general vaccine classification. In part two, it presents representative types of vaccine delivery systems individually with focus on the physicochemical properties of the systems and their significance for the immune response they stimulate. These delivery systems include aluminum adjuvants, emulsions, liposomes, bilosomes, cubosomes/hexosomes, ISCOMs, virus-like particles, polymeric nano- and microparticles, gels, implants and cell-based delivery systems. Following these chapters, part three addresses the challenges associated with vaccine delivery via specific routes of administration—in particular subcutaneous, intramuscular, oral, nasal, pulmonary, transdermal and vaginal administration. Furthermore, the specific administration routes are discussed in combination with device technologies relevant for the respective routes as well as dosage forms appropriate for the device technology. Finally, the fourth part concerns pharmaceutical analysis and quality control of subunit vaccines.
  table of contents: 1 Immunological Background -- 2 Classification of Vaccines -- 3 Aluminum Adjuvants - Basic Concepts and Progress in Understanding -- 4 Emulsions as Vaccine Adjuvants -- 5 The application of liposomes as vaccine adjuvants -- 6 Developing Bilayer-based Delivery Systems for Oral Delivery of Subunit Vaccines -- 7 Cubosomes – Structure, Preparation and Use as an Antigen Delivery System -- 8 ISCOMs as a Vaccine Delivery System -- 9 Virus-like Particles, a Versatile Subunit Vaccine Platform -- 10 Polymeric Particulates for Subunit Vaccine Delivery -- 11 Gels as Vaccine Delivery Systems -- 12 Implants as Sustained Release Delivery Devices for Vaccine Antigens -- 13 Dendritic Cell-based Vaccines -- 14 Parenteral Vaccine Administration – Tried and True -- 15 Nasal Administration of Vaccines -- 16 Pulmonary Administration of Subunit Vaccines -- 17 Vaginal Delivery of Subunit Vaccines -- 18 Transcutaneous Administration -- 19 Pharmaceutical Analysis and Quality Control of Vaccines -- 20 The Physical Analysis of Vaccines -- 21 Characterizing the Association between Antigens and Adjuvants.
  note: edited by Camilla Foged, Thomas Rades, Yvonne Perrie, Sarah Hook.
  subject:
    topic: Medicine
  subject:
    topic: Vaccines
  subject:
    topic: Pharmaceutical technology
  subject:
    topic: Biomedicine
  subject:
    topic: Pharmaceutical Sciences/Technology
  subject:
    topic: Vaccine
  subject:
    topic: Biomedicine general
  classification: RS380
  classification: RS190-210
  classification: 615.19
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Delivery Science and Technology
  identifier: 9781493914173
  identifier: http://dx.doi.org/10.1007/978-1-4939-1417-3
  record info:
    record creation date: 141122
    record change date: 20150519174336.0
    record identifier: 978-1-4939-1417-3