rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Dopamine and Glutamate in Psychiatric Disorders
  name:
    name part: Schmidt, Werner J.
    role:
      role term: editor.
  name:
    name part: Reith, Maarten E. A.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2005
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: online resource.
  abstract: Continous rigorous research in basic neurosciences and in clinical studies has enormously increased our knowledge of the neurobiological basis of mental functions and of the neuronal dysfunctions underlying such diseases as schizophrenia, depression, attention deficit disorder, and Parkinson's disease. A transmitter system does not work in isolation, it interacts with other transmitters and the balance between several transmitter determines the outcome, either physiological or pathological. Such a critical balance exists between dopamine and glutamate, which in many brain areas play functionally opposing roles. In Dopamine and Glutamate in Psychiatric Disorders, a panel of neurochemists, pharmacologists, experimental psychologists, and clinicians summarizes our current understanding of the interactive role of dopamine and glutamate in psychiatric diseases and from that develops novel therapeutic strategies and possibilities for the future. Among the new ideas presented are hypotheses on the role of dopamine and glutamate in aggression, the glutamate system in anxiety disorders, glutamate and neurodegeneration, on the origin, progression, and cognitive aspects of Parkinson's disease. Additional chapters offer illuminating insights into a variety of psychiatric diseases, including attention deficit hyperactivity disorder, stress, aggression, addiction, schizophrenia, depression, social phobias, dementias, bulimia, and neurodegenerative diseases like Parkinson's and Alzheimer's diseases. Each chapter summarizes the prevalence and symptoms of the disease and explains the involvement of dopamine and/or glutamate systems using the newer molecular approaches such as transgenic knockout or knockin mice and recent brain imaging techniques. The authors also offer a critical selection and evaluation of relevant literature and a description of future directions for new therapy development. Path-breaking and insightful, Dopamine and Glutamate in Psychiatric Disorders offers beha…
  table of contents: Dopamine -- Dopamine Receptors -- Dopamine Receptor Alternative Splicing -- Glutamate -- Glutamatergic Pathways -- Glutamate Receptors -- Metabotropic Glutamate Receptors -- Schizophrenia -- Dopamine and Schizophrenia -- Glutamate and Schizophrenia and the N-Methyl-d-Aspartate Receptor Hypofunction Hypothesis -- Role of Glycine in Schizophrenia -- Depression -- Dopamine and Depression -- Glutamate and Depression -- Stress and Aggression -- Dopamine, Glutamate, and Aggression -- Anxiety -- Glutamatergic Systems and Anxiety -- Attention Deficit Hyperactivity Disorder -- Dopamine and Glutamate in Attention Deficit Hyperactivity Disorder -- Addiction -- Dopamine-Glutamate Interactions in Reward-Related Incentive Learning -- Sensitization and Relapse -- Glutamatergic Neurotransmission in Sensitization -- Glutamatergic Mechanisms of Drug Relapse -- Neurodegeneration -- Dopamine and Neurodegeneration -- Glutamate and Neurodegeneration -- Parkinson’s Disease -- Presymptomatic and Symptomatic Stages of Intracerebral Inclusion Body Pathology in Idiopathic Parkinson’s Disease -- Dopamine and Glutamate in Parkinson’s Disease -- Dopamine and Glutamate in Motor and Cognitive Symptoms of Parkinson’s Disease -- Huntington’s Disease -- Dopamine and Glutamate in Huntington’s Disease -- Dementias -- Dopaminergic and Glutamatergic Systems in Alzheimer’s Disease.
  note: edited by Werner J. Schmidt, Maarten E. A. Reith.
  subject:
    topic: Medicine
  subject:
    topic: Psychiatry
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Psychiatry
  classification: RC434.2-574
  classification: 616.89
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781592598526
  identifier: http://dx.doi.org/10.1007/978-1-59259-852-6
  record info:
    record creation date: 100421
    record change date: 20150519185801.0
    record identifier: 978-1-59259-852-6