rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Stem Cells in Endocrinology
  name:
    name part: Lester, Linda B.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2005
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIV, 274 p. online resource.
  abstract: Stem cell research can not only develop potential sources of cells for endocrine therapy, but can also allow the study of organ development ex vivo using isolated and defined stem cell precursors. In Stem Cells in Endocrinology, leading stem cell biologists and developmental endocrinologists critically review both cutting-edge approaches to stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders. Background chapters provide a basic understanding of stem cell biology and introduce all major types of stem cells, including embryonic, adult, cord blood, and germ line. State of the art and forward looking, Stem Cells in Endocrinology offers the basic and clinician scientist an authoritative evaluation of all aspects of how stem cells might be used to create endocrine cells and to treat such diseases as type 1 diabetes.
  table of contents: Basic Stem Cell Biology -- Embryonic Stem Cells -- Germ Line Stem Cells -- Umbilical Cord Stem Cells -- Differentiation Potential of Adult Stem Cells -- Growth Conditions for Primate vs Murine Embryonic Stem Cells -- Translational Research -- Islet Precursor Cells in Adult Pancreatic Islets -- Transcription Factor-Directed Differentiation of Stem Cells Along an Endocrine Lineage -- Generation of Islet-Like Structures From ES Cells -- The Therapeutic Potential of Liver Repopulation for Metabolic or Endocrine Disorders -- The Manipulation of Mesenchymal Stem Cells for Bone Repair -- Spermatogenesis From Transplanted Spermatogenic Stem Cells -- Hematopoietic Stem Cell Transplant in the Treatment of Autoimmune Endocrine Disease -- Preclinical Trials for Stem Cell Therapy.
  note: edited by Linda B. Lester.
  subject:
    topic: Medicine
  subject:
    topic: Endocrinology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Endocrinology
  classification: RC648-665.2
  classification: 616.4
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Contemporary Endocrinology
  identifier: 9781592599004
  identifier: http://dx.doi.org/10.1385/1592599001
  record info:
    record creation date: 100301
    record change date: 20150519175916.0
    record identifier: 978-1-59259-900-4