rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: Leydig Cell in Health and Disease
  name:
    name part: Payne, Anita H.
    role:
      role term: editor.
  name:
    name part: Hardy, Matthew P.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2007
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 476 p. 79 illus., 2 illus. in color. online resource.
  abstract: Nearly ten years after they published the first book devoted entirely to the Leydig cell, Matthew Hardy and Anita Payne have collaborated again to provide a comprehensive study of this fascinating and important cell type. The Leydig Cell in Health and Disease presents all of the developments in our understanding of Leydig cell biology and explores a wide variety of current and potential clinical applications. All aspects of Leydig cell biology, development, regulation, and physiology are explored in thirty-one expertly written chapters. The Leydig Cell in Health and Disease explores topics of great interest to the private sector, including the possible application of steroidogenesis discoveries to androgen synthesis or suppressing Leydig cell function as a key mechnanism in the development of a male contraceptive. This in-depth volume is an invaluable resource for information on the science and application of Leydig cell biology and function.
  table of contents: Historical -- A History of Leydig Cell Research -- Cell Biology -- Structural and Histological Analysis of Leydig Cell Steroidogenic Function -- Fetal Leydig Cells -- Regulation of Leydig Cells During Pubertal Development -- The Human Leydig Cell -- Dynamics of Leydig Cell Regeneration After EDS -- Aging and the Decline of Androgen Production -- Steroidogenesis -- Regulation of Leydig Cell Cholesterol Metabolism -- The Role of StAR in Leydig Cell Steroidogenesis -- Steroidogenic Enzymes in Leydig Cells -- Development of Leydig Cell Steroidogenesis -- Peripheral Testosterone Metabolism -- Leydig Cell Aromatase -- The Role of Estrogen Sulfotransferase in Leydig Cells -- Endocrinology of Leydig Cells in Nonmammalian Vertebrates -- Regulation -- The Luteinizing Hormone Receptor -- Insights Into Leydig Cell Function From Mice With Genetically Modified Gonadotropin Action -- Growth Factors in Leydig Cell Function -- Insulin-Like Peptide 3 in Leydig Cells -- Neuronal Signaling Molecules and Leydig Cells -- Regulation of Leydig Cell Function as it Pertains to the Inflammatory Response -- Activins and Leydig Cell Development Differentiation, and Disease -- Transcription Factors as Regulators of Gene Expression During Leydig Cell Differentiation and Function -- Androgen Receptor in Leydig Cell Function and Development -- Physiology and Applied Aspects -- Fluid Exchange and Transport of Hydrophilic Factors in the Testis -- Immortalized Leydig Cell Lines as Models for Studying Leydig Cell Physiology -- Induction of Leydig Cell Tumors by Xenobiotics -- Environmental Factors That Disrupt Leydig Cell Steroidogenesis -- The Leydig Cell as a Target for Male Contraception -- Clinical Evaluation of Leydig Cell Function.
  note: edited by Anita H. Payne, Matthew P. Hardy.
  subject:
    topic: Medicine
  subject:
    topic: Human physiology
  subject:
    topic: Endocrinology
  subject:
    topic: Cell biology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Endocrinology
  subject:
    topic: Cell Biology
  subject:
    topic: Human Physiology
  classification: RC648-665.2
  classification: 616.4
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Contemporary Endocrinology
  identifier: 9781597454537
  identifier: http://dx.doi.org/10.1007/978-1-59745-453-7
  record info:
    record creation date: 100301
    record change date: 20151204181814.0
    record identifier: 978-1-59745-453-7