rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Vitamin D
    sub title: Physiology, Molecular Biology, and Clinical Applications
  name:
    name part: Holick, Michael F.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2010
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XXVI, 1160 p. 241 illus., 7 illus. in color. online resource.
  abstract: In Vitamin D: Physiology, Molecular Biology, and Clinical Applications, Second Edition, leading researchers provide a comprehensive, highly readable overview of the biological functions and clinical applications of vitamin D and its metabolites. Topics range from the most recent recommendations for vitamin D intake to new approaches for the treatment and prevention of vitamin D deficiency and the development of active vitamin D drugs to treat psoriasis and cancer. The book demonstrates the significant role that vitamin D has in maintaining good bone health and the prevention of osteoporosis, an important health problem for adults over the age of fifty. In addition, it authoritatively reviews the relationship between sunlight exposure, vitamin D, and increased risk of colon and breast cancer; how vitamin D is made in the skin; and the sequence of events that leads to its activation by the kidney. Also examined are the biological functions of 1,25-dihydrovitamin D3 on the intestine and bone, as well as other tissues, such as skin, the immune system, prostate, and breast, and vitamin D's molecular mechanism of action on the cell membrane and nucleus. The first edition of Vitamin D: Physiology, Molecular Biology and Clinical Applications was the benchmark in the field when published in 1999. This new and expanded volume continues to include extensive, in-depth chapters covering the most important aspects of the complex interactions between vitamin D and other dietary components, the ongoing debate concerning the best indicator of optimal vitamin D status and its nutrient requirements, and the impact of less than optimal status on disease risk. Vitamin D: Physiology, Molecular Biology, and Clinical Applications, Second Edition is designed and organized not only to be an up-to-date review on the subject, but also to provide medical students, graduate students, health care professionals and even the lay public with a reference source for the most up-to-date information abo…
  table of contents: and Basic Biology -- Vitamin D and Health: Evolution, Biologic Functions, and Recommended Dietary Intakes for Vitamin D -- Photobiology of Vitamin D -- The Functional Metabolism and Molecular Biology of Vitamin D Action -- Metabolism and Catabolism of Vitamin D, Its Metabolites and Clinically Relevant Analogs -- The Molecular Biology of the Vitamin D Receptor -- VDR and RXR Subcellular Trafficking -- Mechanism of Action of 1,25-Dihydroxyvitamin D3 on Intestinal Calcium Absorption and Renal Calcium Transport -- Biological and Molecular Effects of Vitamin D on Bone -- Biological and Molecular Effects of Vitamin D on the Kidney -- Vitamin D and the Parathyroids -- Diversity of Vitamin D Target Genes -- Non-skeletal/Functions of Vitamin D -- Extrarenal Synthesis of 1,25-Dihydroxyvitamin D and Its Health Implications -- Vitamin D and the Innate Immunity -- Vitamin D and Colon Cancer -- Mechanisms of Resistance to Vitamin D Action in Human Cancer Cells -- Vitamin D and the Brain: A Neuropsychiatric Perspective -- Vitamin D Modulation of Adipocyte Function -- Vitamin D Status – Global Analysis -- Determinants of Vitamin D Intake -- 25-Hydroxyvitamin D Assays and Their Clinical Utility -- Health Disparities and Vitamin D -- Vitamin D Deficiency in Canada -- Vitamin D Deficiency and Its Health Consequences in Northern Europe -- Vitamin D Deficiency and Consequences for the Health of People in Mediterranean Countries -- Vitamin D Deficiency in the Middle East and Its Health Consequences -- Vitamin D Deficiency in the Middle East and Its Health Consequences for Adults -- Vitamin D Deficiency and Its Health Consequences in Africa -- Vitamin D Deficiency and Its Health Consequences in India -- Vitamin D Deficiency, Rickets, and Fluorosis in India -- Vitamin D in Asia -- Vitamin D Deficiency and Its Health Consequences in New Zealand -- Toxicity of Vitamin D -- Health Consequences of Vitamin D Deficiency and Resistance on Musculo Skeletal Health -- Vitamin D Deficiency in Pregnan…
  note: edited by Michael F. Holick.
  subject:
    topic: Medicine
  subject:
    topic: Nutrition
  subject:
    topic: Public health
  subject:
    topic: Internal medicine
  subject:
    topic: Endocrinology
  subject:
    topic: Clinical nutrition
  subject:
    topic: Biochemistry
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Public Health
  subject:
    topic: Clinical Nutrition
  subject:
    topic: Nutrition
  subject:
    topic: Endocrinology
  subject:
    topic: Internal Medicine
  subject:
    topic: Biochemistry, general
  classification: RA1-1270
  classification: 613
  classification: 614
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Nutrition and Health
  identifier: 9781603273039
  identifier: http://dx.doi.org/10.1007/978-1-60327-303-9
  record info:
    record creation date: 100628
    record change date: 20151204162652.0
    record identifier: 978-1-60327-303-9