rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Membrane Receptors, Channels and Transporters in Pulmonary Circulation
  name:
    name part: Yuan, Jason X. -J.
    role:
      role term: editor.
  name:
    name part: Ward, Jeremy P. T.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2010
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVI, 501 p. online resource.
  abstract: Membrane Receptors, Channels and Transporters in Pulmonary Circulation is a proceeding of the 2008 Grover Conference (Lost Valley Ranch and Conference Center, Sedalia, Colorado; September 3-7, 2008), which provided a forum for experts in the fields of those receptors, channels and transporters that have been identified as playing key roles in the physiology and pathophysiology of the pulmonary circulation. The book rigorously addresses: i) recent advances in our knowledge of receptors, channels and transporters and their role in regulation of pulmonary vascular function; ii) how modulation of expression and function of receptors, channels and transporters and their interrelationships contribute to the pathogenesis of pulmonary vascular disease; and iii) the therapeutic opportunities that may be revealed by enhancing our understanding of this area. The overall goal was to explore the mechanisms by which specific receptors, channels and transporters contribute to pulmonary vascular function in both health and disease, and how this knowledge may lead to novel interventions in lung dysplasia, pulmonary edema, lung injury, and pulmonary and systemic hypertension to reduce and prevent death from lung disease. Membrane Receptors, Channels and Transporters in Pulmonary Circulation is divided into six parts. Part 1 (Ion Channels in the Pulmonary Vasculature: Basics and New Findings) is designated for basic knowledge and recent findings in the research field of ion channels in pulmonary circulation. There are five chapters in Part I discussing the function, expression, distribution and regulation of various ion channels present in pulmonary vascular smooth muscle cells and how these channels are integrated to regulate intracellular Ca2+ and cell functions. Part II (TRP Channels in the Pulmonary Vasculature: Basics and New Findings) is composed of five chapters that are exclusively designed to discuss the role of a recently identified family of cation channels, transient recep…
  table of contents: Ion Channels in the Pulmonary Vasculature: Basics and New Findings -- The Role of Ion Channels in Hypoxic Pulmonary Vasoconstriction -- Two-Pore Domain K+ Channels and Their Role in Chemoreception -- Intricate Interaction Between Store-Operated Calcium Entry and Calcium-Activated Chloride Channels in Pulmonary Artery Smooth Muscle Cells -- The Role of Intracellular Ion Channels in Regulating Cytoplasmic Calcium in Pulmonary Arterial Smooth Muscle: Which Store and Where? -- Ca2+ Oscillations Regulate Contraction Of Intrapulmonary Smooth Muscle Cells -- TRP Channels in the Pulmonary Vasculature: Basics and New Findings -- to TRP Channels: Structure, Function, and Regulation -- Physiological Functions of Transient Receptor Potential Channels in Pulmonary Arterial Smooth Muscle Cells -- The Contribution of TRPC1 and STIM1 to Capacitative Ca2+ Entry in Pulmonary Artery -- Store-Operated Calcium Entry Channels in Pulmonary Endothelium: The Emerging Story of TRPCS and Orai1 -- TRPM2 Channel Regulates Endothelial Barrier Function -- Pathogenic Role of Ion Channels in Pulmonary Vascular Disease -- A Proposed Mitochondrial–Metabolic Mechanism for Initiation and Maintenance of Pulmonary Arterial Hypertension in Fawn-Hooded Rats: The Warburg Model of Pulmonary Arterial Hypertension -- The Role of Classical Transient Receptor Potential Channels in the Regulation of Hypoxic Pulmonary Vasoconstriction -- Developmental Regulation of Oxygen Sensing and Ion Channels in the Pulmonary Vasculature -- Hypoxic Regulation of Ion Channels and Transporters in Pulmonary Vascular Smooth Muscle -- CLC-3 Chloride Channels in the Pulmonary Vasculature -- Receptors and Signaling Cascades in Pulmonary Arterial Hypertension -- Role of Bone Morphogenetic Protein Receptors in the Development of Pulmonary Arterial Hypertension -- Cross Talk Between Smad, MAPK, and Actin in the Etiology of Pulmonary Arterial Hypertension -- Notch Signaling in Pulmonary Hypertension -- Rho Kinase-Mediated Vasoconstrictio…
  note: edited by Jason X. -J. Yuan, Jeremy P. T. Ward.
  subject:
    topic: Medicine
  subject:
    topic: Medical biochemistry
  subject:
    topic: Vascular surgery
  subject:
    topic: Cell biology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Vascular Surgery
  subject:
    topic: Cell Biology
  subject:
    topic: Medical Biochemistry
  classification: RD598.5-598.7
  classification: 617.413
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Experimental Medicine and Biology, 661
  identifier: 9781607615002
  identifier: http://dx.doi.org/10.1007/978-1-60761-500-2
  record info:
    record creation date: 100316
    record change date: 20151204152051.0
    record identifier: 978-1-60761-500-2