rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Studies on Experimental Models
  name:
    name part: Basu, Samar.
    role:
      role term: editor.
  name:
    name part: Wiklund, Lars.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2011
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XX, 698 p. 111 illus., 52 illus. in color. online resource.
  abstract: There is a widespread consensus that use of antioxidants as a therapeutic approach may counteract free radical mediated pathologies. However, the role of antioxidants in normal physiology and redox signaling is still in its infancy. Since oxidative stress is related to various diseases and pathologies, scientists are eager to study the disease in humans, but it is not always ethical to study all the aspects of the disease in humans. Thus, it becomes mandatory to study the disease process and the mechanisms behind it through experimental models which generally involve animals, in vitro/cell culture studies, primates and even humans to a certain extent. Studies on Experimental Models contains data on the experimental models or review of such models of oxidative stress in various diseases. It is structured into six sections, which are as follows: diabetes, cardiovascular, neurology, ocular diseases, toxicology/environmental and in vitro/tissue culture. Each section presents a sketch of models in humans, animals and in vitro methods. Taken together, they comprise a valuable reference for basic and clinical scientists, one aimed at contributing to the advancement of oxidative stress research using appropriate animal models.
  table of contents: DIABETES -- Role of Oxidative Stress and Targeted Antioxidant Therapies in Experimental Models of Diabetic Complications -- Experimental Models of Oxidative Stress Related to Cardiovascular Diseases and Diabetes -- CARDIOVASCULAR -- Arachidonic Acid Metabolism and Lipid Peroxidation in Stroke: Alpha-tocotrienol as a Unique Therapeutic Agent -- Assessment of Oxidative Stress in the Brain of Spontaneously Hypertensive Rat and Stroke-Prone Spontaneously Hypertensive Rat Using by Electron Spin Resonance Spectroscopy -- Small Heat Shock Proteins and Doxorubicin-induced Oxidative Stress in The Heart -- Oxidative Stress in Cardiovascular Disease: Potential Biomarkers and Their Measurements -- In vivo Imaging of Antioxidant Effects on NF-kappaB Activity in Reporter Mice -- NEUROLOGY -- MPTP and Oxidative Stress: It’s Complicated! -- Oxidative Stress in Alzheimer´s Disease: A Critical Appraisal of the Causes and the Consequences -- Retinal Disturbances in Patients and Animal Models with Huntington’s, Parkinson’s and Alzheimer’s Disease -- Stress Gene Deregulation in Alzheimer Peripheral Blood Mononuclear Cells -- The Use of Gpx4 Knockout Mice and Transgenic Mice to Study the Roles of Lipid Peroxidation in Diseases and Aging -- An Experimental Model of Myocardial and Cerebral Global Ischemia and Reperfusion -- OCULAR DISEASES -- Neovascular Models of the Rabbit Eye Induced by Lipid Hydroperoxide -- Purinergic Signaling Involved in the Volume Regulation of Glial Cells in the Rat Retina: Alteration in Experimental Diabetes -- TOXICOLOGY / ENVIRONMENTAL -- Helicobacter Pylori-induced Oxidative stress and Inflammation -- Experimental Models for Ionizing Radiation Research -- Experimental Models to Study Cigarette Smoke-Induced Oxidative Stress In Vitro and In Vivo in Pre-Clinical Models, and in Smokers and Patients with Airways Disease -- Exhaled Breath Condensate Biomarkers of Airway Inflammation and Oxidative Stress in COPD -- Induction of Oxidative Stress by Iron/Ascorbate in …
  note: edited by Samar Basu, Lars Wiklund.
  subject:
    topic: Life sciences
  subject:
    topic: Veterinary medicine
  subject:
    topic: Biochemistry
  subject:
    topic: Cell biology
  subject:
    topic: Oxidative stress
  subject:
    topic: Zoology
  subject:
    topic: Life Sciences
  subject:
    topic: Oxidative Stress
  subject:
    topic: Cell Biology
  subject:
    topic: Animal Biochemistry
  subject:
    topic: Veterinary Medicine
  subject:
    topic: Zoology
  classification: QH573-671
  classification: 571.9453
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Oxidative Stress in Applied Basic Research and Clinical Practice
  identifier: 9781607619567
  identifier: http://dx.doi.org/10.1007/978-1-60761-956-7
  record info:
    record creation date: 110411
    record change date: 20151030021244.0
    record identifier: 978-1-60761-956-7