rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Translational Stem Cell Research
    sub title: Issues Beyond the Debate on the Moral Status of the Human Embryo
  name:
    name part: Hug, Kristina.
    role:
      role term: editor.
  name:
    name part: Hermerén, Göran.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2011
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XXVI, 462 p. online resource.
  abstract: For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. Translational Stem Cell Research is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma. Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications.
  table of contents: PREFACE -- BIOSKETCHES -- SECTION I: TRANSLATIONAL STEM CELL RESEARCH: WHAT IS POSSIBLE TODAY AND WHAT STILL REMAINS TO BE ACHIEVED?- Chapter 1. Towards clinical application of stem cells in neurodegenerative disorders (Olle Lindvall and Zaal Kokaia) -- Chapter 2. Treating cardiac disorders with stem cells (Christine Mummery) -- Chapter 3. Treating diabetes (Mattias Hansson and Ole D. Madsen) -- Chapter 4. Treating oncologic diseases (Peter W. Andrews) -- Chapter 5. Clinical application of autologous epithelial stem cells in disorders of squamous epithelia (Nicolas Grasset and Yann Barrandon) -- Chapter 6. Towards a cell therapy for Muscular Dystrophy: technical and ethical issues (Giulio Cossu) -- Chapter 7. Towards modelling and therapy of genetic diseases using pluripotent stem cells (Petr Dvorak) -- Chapter 8. Therapeutic possibilities of induced pluripotent stem cells (Harold Ayetey) -- Chapter 9. Industrial applications of stem cells (Oliver Brüstle, Michael Rossbach and Manal Bosnali) -- Chapter 10. The obstacles on the road to clinical applications of stem cell-based therapies: What has been done to overcome these obstacles and what remains to be done? (Outi Hovatta) -- SECTION II. TRANSLATING STEM CELL RESEARCH KNOWLEDGE FROM BENCH TO BEDSIDE: ETHICAL ISSUES -- Chapter 11. Animal use in translational stem cell research and treatment development: Ethical issues (Kate Millar) -- Chapter 12. Ethical aspects of stem cell-based clinical translation: research, innovation, and delivering unproven interventions (Jeremy Sugarman and Doug Sipp) -- Chapter 13. Translational stem cell research in pediatrics: Ethical issues (Michael Fuchs) -- Chapter 14. Experimental stem cell-based therapy in pediatrics: A fictional case study (Kristina Hug and Anders Castor) -- SECTION III: CREATION OF HUMAN-ANIMAL ENTITIES FOR TRANSLATIONAL STEM CELL RESEARCH: SCIENTIFIC, ETHICAL AND REGULATORY CHALLENGES -- Chapter 15. Creation of human-animal entities for translational stem cell re…
  note: edited by Kristina Hug, Göran Hermerén.
  subject:
    topic: Life sciences
  subject:
    topic: Stem cells
  subject:
    topic: Life Sciences
  subject:
    topic: Stem Cells
  classification: QH588.S83
  classification: 571.6
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Stem Cell Biology and Regenerative Medicine
  identifier: 9781607619598
  identifier: http://dx.doi.org/10.1007/978-1-60761-959-8
  record info:
    record creation date: 101222
    record change date: 20150519184053.0
    record identifier: 978-1-60761-959-8