rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Studies on Alzheimer's Disease
  name:
    name part: Praticὸ, Domenico.
    role:
      role term: editor.
  name:
    name part: Mecocci, Patrizia.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxu
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XI, 236 p. 34 illus., 29 illus. in color. online resource.
  abstract: Dr. Domenico Praticò received his M.D. from the University of Rome “La Sapienza,” School of Medicine. He is currently a Professor of Pharmacology, Microbiology and Immunology and member of the Center for Translational Medicine at Temple University. His main research interest is oxidative biology with a particular focus on bioactive lipids, their metabolic pathways, and their role as biological mediators of cellular and molecular events in the pathogenesis of human diseases, including neurodegenerative and cardiovascular diseases. Dr. Patrizia Mecocci received her M.D. from the University of Perugia, School of Medicine. She is currently a Full Professor of Gerontology and Geriatrics and Director of the Geriatric Clinic at the University of Perugia. Her research is devoted mainly to clinical geriatrics, with a specific interest on brain aging and dementia and on age-related biological modifications, with a particular focus on the role of oxidants and antioxidants in neurodegenerative and cardiovascular diseases. .
  table of contents: Section 1: Hypotheses -- Oxidative stress: impact in neuroscience research -- Oxidative stress and Alzheimer’s disease -- Inflammation and Oxidation: a link in Alzheimer’ disease pathogenesis -- GAPDH:β-amyloid mediated iron accumulation in Alzheimer’s disease -- Aβ in mitochondria: one piece in the Alzheimer’s disease puzzle -- The role of the plasma membrane redox system in the pathognesis of Alzheimer’s disease -- Section 2: Mechanisms -- Metal dysfunction in Alzheimer’s disease -- Brain Oxidative Stress in the Pathogenesis and Progression of Alzheimer’s Disease -- Cholesterol metabolism and oxidative stress in Alzheimer’s disease -- Brain hypometabolism, oxidative stress, maternal transmission and risk of late-onset Alzheimer’s disease -- Stress and HPA axis dysfunction in Alzheimer’s disease -- Section 3: Clinics -- Diabetes mellitus and its impact on sporadic Alzheimer’s disease -- Peripheral biomarkers of oxidative tress in Alzheimer’s disease -- Nutrition lifestyle and oxidative stress: prevention in Alzheimer’s disease -- Are antioxidants food and nutrients useful in preventing cognitive decline?.- Antioxidant clinical trials in Mild Cognitive Impairment and Alzheimer’s disease.
  note: edited by Domenico Praticὸ, Patrizia Mecocci.
  subject:
    topic: Life sciences
  subject:
    topic: Geriatrics
  subject:
    topic: Cell biology
  subject:
    topic: Oxidative stress
  subject:
    topic: Life Sciences
  subject:
    topic: Oxidative Stress
  subject:
    topic: Cell Biology
  subject:
    topic: Geriatrics/Gerontology
  classification: QH573-671
  classification: 571.9453
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Oxidative Stress in Applied Basic Research and Clinical Practice
  identifier: 9781627035989
  identifier: http://dx.doi.org/10.1007/978-1-62703-598-9
  record info:
    record creation date: 130921
    record change date: 20151030111516.0
    record identifier: 978-1-62703-598-9