rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Combination Therapy in Hypertension
  name:
    name part: Neutel, Joel M.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: xxk
    date issued: 2011
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VII, 84 p. 43 illus., 3 illus. in color. online resource.
  abstract: For over 30 years, the stepped care approach has been used in the management and treatment of hypertension. This approach advocates the use of initial monotherapy to reach the desired blood pressure, and the subsequent use of additional drugs with complementary modes of action, until the target BP is achieved. However, current control rates for hypertension suggest that such an approach may be outdated and no longer effective in the management of hypertension. Clinical trials have shown that more than 50% of patients require a combination of drug therapies to achieve their target BP. Some proponents of combination therapy have argued that the risk of adverse side effects and non-compliance will be lower than that compared to monotherapy, which initially requires higher doses to be administered to be effective. Consequently, there have been increasing calls of the necessity for a much more combined approach in the treatment of hypertension. Adding to this, Combination Therapy in Hypertension will cover current control rates of blood pressure worldwide, the benefits of monotherapy and combination therapy, examine the effectiveness, risk of adverse effects, compliance, and cost of the available therapies and will also include information on relevant outcome studies.
  table of contents: 1. State of Hypertension Control in 2007 -- 2. Historical Review of Combination Therapy -- 3. Advantages of Combination Therapy and Monotherapy -- 4. Use of Combination Therapy and Monotherapy -- 5. Outcome Studies with Combination Therapy -- 6. USe of Combination Therapy as First Line Treatment -- 7. Available Combination Agents.
  note: by Joel M. Neutel.
  subject:
    topic: Medicine
  subject:
    topic: General practice (Medicine)
  subject:
    topic: Angiology
  subject:
    topic: Cardiology
  subject:
    topic: Primary care (Medicine)
  subject:
    topic: Pharmacotherapy
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Cardiology
  subject:
    topic: Pharmacotherapy
  subject:
    topic: Primary Care Medicine
  subject:
    topic: Angiology
  subject:
    topic: General Practice / Family Medicine
  classification: RC681-688.2
  classification: 616.12
  related item:
    title info:
      title: Springer eBooks
  identifier: 9781908517289
  identifier: http://dx.doi.org/10.1007/978-1-908517-28-9
  record info:
    record creation date: 131217
    record change date: 20151204154157.0
    record identifier: 978-1-908517-28-9