rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Congenital Hyperinsulinism
    sub title: A Practical Guide to Diagnosis and Management
  name:
    name part: De León-Crutchlow, Diva D.
    role:
      role term: editor.
    role:
      role term: edt
    role:
      role term: http://id.loc.gov/vocabulary/relators/edt
  name:
    name part: Stanley, Charles A.
    role:
      role term: editor.
    role:
      role term: edt
    role:
      role term: http://id.loc.gov/vocabulary/relators/edt
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2019
    edition: 1st ed. 2019.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XV, 165 p. 22 illus., 12 illus. in color. online resource.
  abstract: This unique book is a practical guide for the clinician faced with the challenge of diagnosing and managing neonates, infants and children with congenital hyperinsulinism (HI), within the framework of pathophysiology and molecular genetics. Major advances have been made in HI research over the past two decades, and with this better understanding of the molecular genetics of HI, a "personalized" approach to management according to the type of hyperinsulinism, and particularly according to the likelihood of focal hyperinsulinism, is starting to emerge. The opening chapter discusses HI diagnosis using biochemical approaches and phenotype characterization. The various forms of HI are then presented in detail in three main categories: diazoxide-responsive, diazoxide-unresponsive and syndromic HI. Both medical and surgical management strategies are then discussed, covering imaging, histology, surgical approach, and post-operative management. Complications, such as feeding problems, and long-term outcomes, such as neurodevelopmental issues, are carefully considered in the final chapter. Practical and user-friendly, Congenital Hyperinsulinism is the go-to resource for pediatric endocrinologists, residents and fellows, general pediatricians and neonatologists.
  table of contents: Approach to the Diagnosis of Neonates and Infants with Persistent Hypoglycemia -- Diazoxide-Responsive Forms of Congenital Hyperinsulinism -- Diazoxide-Unresponsive Forms of Congenital Hyperinsulinism -- Syndromic Causes of Congenital Hyperinsulinism -- Molecular Diagnosis of Congenital Hyperinsulinism -- Medical Management of Hyperinsulinism -- 18F-DOPA PET -- Histopathology of the Pancreas in Congenital Hyperinsulinism -- Surgery for Congenital Hyperinsulinism -- Perioperative Management of Hyperinsulinism -- Management of the Child with Persistent Hypoglycemia After Surgery -- Management of Diabetes and Pancreatic Insufficiency after Pancreatectomy -- Feeding Problems in Congenital Hyperinsulinism -- Neurodevelopmental Outcomes.
  note: edited by Diva D. De León-Crutchlow, Charles A. Stanley.
  subject:
    topic: Endocrinology
  subject:
    topic: Pediatrics
  subject:
    topic: Endocrinology
  subject:
    topic: Pediatrics
  classification: RC648-665.2
  classification: 616.4
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Contemporary Endocrinology
  identifier: 9783030029616
  identifier: https://doi.org/10.1007/978-3-030-02961-6
  record info:
    record creation date: 190104
    record change date: 20191023162504.0
    record identifier: 978-3-030-02961-6