The mRNA Metabolism in Human Disease

• Corporate Author: SpringerLink (Online service)
• Other Authors: Romão, Luísa (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Series: Advances in Experimental Medicine and Biology, 1157
• Subjects: Human genetics.; Cancer research.; Molecular biology.; Nucleic acids.; Human Genetics.; Cancer Research.; Molecular Medicine.; Nucleic Acid Chemistry.

The eukaryotic gene expression pathway involves a number of interlinked steps, with messenger RNA (mRNA) being the key intermediate. The precursor mRNA is transcribed from DNA, processed by removal of introns and addition of the cap structure and the poly(A) tail. The mature mRNA is then exported to...