rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Structural and Biochemical Characterization of the YaxAB Pore-forming Toxin from Yersinia Enterocolitica
  name:
    name part: Bräuning, Bastian.
    role:
      role term: creator
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2019
    edition: 1st ed. 2019.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XXXI, 86 p. online resource.
  abstract: This book discusses the decoding of the lytic mechanism of an α-helical pore-forming toxin, YaxAB, composed of two different subunits. Pore-forming toxins (PFTs) are among the most common bacterial toxins. They are produced by a variety of pathogens, which infect a wide range of organisms including plants, insects and humans. Yet the maturation of these particles and the structural changes required for pore formation are still poorly understood for many PFT families. Using a diverse panel of biochemical and structural techniques, including X-ray crystallography and cryo-electron microscopy, Dr. Bräuning and colleagues have succeeded in identifying the mechanistic contributions of the two toxin components and elucidating the lytic state of the pore complex. The results of this thesis on the YaxAB system are applicable to orthologues from agriculturally relevant insect pathogens, and offer valuable structural and mechanistic insights to inform future bioengineering efforts. .
  table of contents: Introduction -- Objectives -- Materials & Methods -- Results -- Discussion.
  note: by Bastian Bräuning.
  subject:
    topic: Microbiology
  subject:
    topic: Proteins
  subject:
    topic: Analytical chemistry
  subject:
    topic: Biochemical engineering
  subject:
    topic: Bacteriology
  subject:
    topic: Applied Microbiology
  subject:
    topic: Protein Science
  subject:
    topic: Analytical Chemistry
  subject:
    topic: Biochemical Engineering
  subject:
    topic: Bacteriology
  classification: QR1-502
  classification: 660.62
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Springer Theses, Recognizing Outstanding Ph.D. Research
  identifier: 9783030294397
  identifier: https://doi.org/10.1007/978-3-030-29439-7
  record info:
    record creation date: 190926
    record change date: 20191026142735.0
    record identifier: 978-3-030-29439-7