The Biology of mRNA: Structure and Function

• Corporate Author: SpringerLink (Online service)
• Other Authors: Oeffinger, Marlene (Editor, http://id.loc.gov/vocabulary/relators/edt), Zenklusen, Daniel (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Series: Advances in Experimental Medicine and Biology, 1203
• Subjects: Molecular biology.; Gene expression.; Proteins .; Neurosciences.; Posttranslational modification.; Molecular Medicine.; Gene Expression.; Protein-Ligand Interactions.; Posttranslational Modification.

The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space depends on many processes acting...

Table of Contents:

• Regulation of co-transcriptional mRNP assembly
• mRNA export through the NPC
• Roles of mRNA modifications in gene regulation
• Studying mRNPs using single molecule approaches
• Difference between mRNPs and lncRNAs?
• RNPs and/or sequence motives in mRNA localization
• mRNP structure
• New RNA binding proteins: mRNP composition
• Aggregation of repeats RNAs in neurodegenerative diseases
• mRNA structural organization and translation
• How to decide to make an mRNA - degradation
• Methods to study mRNP composition
• mRNA-DNA kisses - R-loops
• Forms of mRNA editing and their role in disease.