rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Endothelial Dysfunction and Inflammation
  name:
    name part: Dauphinee, Shauna.
    role:
      role term: editor.
  name:
    name part: Karsan, Aly.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: sz
    date issued: 2010
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 234 p. online resource.
  abstract: Endothelial dysfunction is broadly defined as a disruption of the balance between vasoactive mediators and a propensity towards an inflammatory state. This volume provides an overview of the fields of endothelial dysfunction and inflammation through the discussion of topics ranging from the molecular biology of activated endothelial cells to the endothelium in inflammatory disease and therapeutic approaches targeting endothelial dysfunction. Topics include: - Heterogeneity of the endothelium during inflammation - Oxidative stress and endothelial dysfunction - Biology and regulation of nitric oxide in inflammatory pathologies - Endothelial dysfunction in inflammatory diseases, such as diabetes and atherosclerosis - Clinical methods used to assess endothelial function This book brings together basic and clinical research to assist the reader in bridging connections from bench-to-bedside. Written by expert researchers in the fields of endothelial biology, inflammation research and clinical science, it serves as a useful reference for academic and industrial researchers, clinicians, and trainees in the medical profession.
  table of contents: Endothelial activation and dysfunction in sepsis -- Heterogeneity in responses of microvascular endothelial cells during inflammation -- Oxidative stress and endothelial dysfunction -- Post-translational regulation of eNOS activity in inflammation -- Endothelial dysfunction in pulmonary hypertension -- Endothelial dysfunction in systemic hypertension -- Sphingosine-1-phosphate as a mediator of endothelial dysfunction during inflammation -- Dissecting TNF-TNFR1/TNFR2 signaling pathways in vasculature -- AGE-RAGE signalling in endothelial dysfunction and atherosclerosis in diabetes -- Regional predisposition to atherosclerosis – An interplay between local hemodynamics, endothelial cells and resident intimal dendritic cells -- Inflammation and endothelial dysfunction with aging -- Clinical approaches to assess endothelial function in vivo -- Therapeutic approaches towards targeting endothelial dysfunction.
  note: edited by Shauna Dauphinee, Aly Karsan.
  subject:
    topic: Medicine
  subject:
    topic: Immunology
  subject:
    topic: Pharmacology
  subject:
    topic: Medical biochemistry
  subject:
    topic: Cell biology
  subject:
    topic: Oxidative stress
  subject:
    topic: Biomedicine
  subject:
    topic: Immunology
  subject:
    topic: Oxidative Stress
  subject:
    topic: Medical Biochemistry
  subject:
    topic: Cell Biology
  subject:
    topic: Pharmacology/Toxicology
  classification: QR180-189.5
  classification: 616.079
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Progress in Inflammation Research
  identifier: 9783034601689
  identifier: http://dx.doi.org/10.1007/978-3-0346-0168-9
  record info:
    record creation date: 110514
    record change date: 20151029231543.0
    record identifier: 978-3-0346-0168-9