rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Untranslated Gene Regions and Other Non-coding Elements
    sub title: Regulation of Eukaryotic Gene Expression
  name:
    name part: Barrett, Lucy W.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Fletcher, Sue.
    role:
      role term: author.
  name:
    name part: Wilton, Steve D.
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: sz
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VIII, 56 p. 2 illus. in color. online resource.
  abstract: There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.
  table of contents: Introduction -- Promoter -- 5’ Untranslated Region -- Structure -- Intronic Regions -- 3’ Untranslated Region -- Non-coding RNAs -- Conclusion.
  note: by Lucy W. Barrett, Sue Fletcher, Steve D. Wilton.
  subject:
    topic: Life sciences
  subject:
    topic: Medical genetics
  subject:
    topic: Nucleic acids
  subject:
    topic: Plant genetics
  subject:
    topic: Animal genetics
  subject:
    topic: Life Sciences
  subject:
    topic: Animal Genetics and Genomics
  subject:
    topic: Plant Genetics & Genomics
  subject:
    topic: Gene Function
  subject:
    topic: Nucleic Acid Chemistry
  classification: QH432
  classification: 591.35
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: SpringerBriefs in Biochemistry and Molecular Biology
  identifier: 9783034806794
  identifier: http://dx.doi.org/10.1007/978-3-0348-0679-4
  record info:
    record creation date: 130628
    record change date: 20151103123201.0
    record identifier: 978-3-0348-0679-4