rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Advancements of Mass Spectrometry in Biomedical Research
  name:
    name part: Woods, Alisa G.
    role:
      role term: editor.
  name:
    name part: Darie, Costel C.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2014
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVI, 600 p. 173 illus., 126 illus. in color. online resource.
  abstract: This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.
  table of contents: Mass Spectrometry for Proteomics-based Investigation -- MALDI profiling and applications in medicine -- Simplifying the proteome: Analytical strategies for improving peak capacity -- Quantitative Shotgun Proteomics with Data-Independent Acquisition and Traveling Wave Ion Mobility Spectrometry: A Versatile Tool in the Life Sciences -- Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) for Quantitative Proteomics -- Utility of Computational Structural Biology in Mass Spectrometry -- Affinity – Mass Spectrometry Approaches for Elucidating Structures and Interactions of Protein – Ligand Complexes -- Neurological Analyses: Focus on Gangliosides and Mass Spectrometry -- Mass Spectrometric Analysis of Post-translational Modifications (PTMs) and Protein-Protein Interactions (PPIs) -- Applications for Mass Spectrometry in the Study of Ion Channel Structure and Function -- A Mass Spectrometry View of Stable and Transient Protein Interactions -- Mass Spectrometry-Based Tissue Imaging of Small Molecules -- Redox Proteomics: from Bench to Bedside -- Analysis of Fluorinated Proteins by Mass Spectrometry -- Mass Spectrometry for Proteomics-Based Investigation Using the Zebrafish Vertebrate Model System -- Mass Spectrometry-Based Biomarkers in Drug Development -- Detection of Bio medically Relevant Stilbenes from Wines by Mass Spectrometry -- Mass Spectrometric DNA Adduct Quantification by Multiple Reaction Monitoring and its Future Use for the Molecular Epidemiology of Cancer -- Using Breast Milk to Assess Breast Cancer Risk: The Role of Mass Spectrometry-Based Proteomics -- Cancer Secretomes and their Place in Supplementing other Hallmarks of Cancer -- Thiostrepton, a Natural Compound that Triggers Heat Shock Response and Apoptosis in Human Cancer Cells: a Proteomics Investigation -- Using Proteomics to Unravel the Mysterious Steps of the HBV life-cycle -- Oxidative Stress and Antibiotic Resistance in Bacterial Pathogens: State of the Art, Methodologies and Future Tre…
  note: edited by Alisa G. Woods, Costel C. Darie.
  subject:
    topic: Chemistry
  subject:
    topic: Mass spectrometry
  subject:
    topic: Proteomics
  subject:
    topic: Chemistry
  subject:
    topic: Mass Spectrometry
  subject:
    topic: Proteomics
  subject:
    topic: Biomedicine general
  classification: QD96.M3
  classification: 543.65
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Experimental Medicine and Biology, 806
  identifier: 9783319060682
  identifier: http://dx.doi.org/10.1007/978-3-319-06068-2
  record info:
    record creation date: 140620
    record change date: 20151030211123.0
    record identifier: 978-3-319-06068-2