http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Novel Macromolecular Architectures via a Combination of Cyclodextrin Host/Guest Complexation and RAFT Polymerization
XXIII, 202 p. 109 illus., 21 illus. in color. online resource.
In this thesis, Bernhard Schmidt describes his research into two fields in the chemical sciences: supramolecular and macromolecular chemistry. Schmidt first investigates cyclodextrins (CDs), which are well know for the formation of supramolecular host/guest complexes with hydrophobic molecules in aqueous solution. Schmidt then also examines reversible addition-fragmentation chain transfer (RAFT) polymerization as a well-suited toll for the synthesis of water-soluble end-funcitonalized polymers. The author skilfully combines both concepts as a powerful tool to access reversibly forming macromolecular architectures. The novel methods and architectures presented in this work are highly interesting from both a fundamental point of view as well as a basis for the design of efficient drug release systems. The work in this thesis has led to a number of publications in top peer-reviewed journals.
Theoretical Background and Literature Overview -- CD-Complexed RAFT Agents -- Supramolecular ABA Triblock Copolymers -- Supramolecular Three Armed Star Polymers -- AB2 Miktoarm Star Polymers -- Modulation of the Thermoresponsitivity of PDEAAm via CD Addition -- Conclusions and Outlook -- Experimental Part.
Springer Theses, Recognizing Outstanding Ph.D. Research