rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Carbohydrates as Drugs
  name:
    name part: Seeberger, Peter H.
    role:
      role term: editor.
  name:
    name part: Rademacher, Christoph.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2014
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VII, 237 p. 112 illus., 44 illus. in color. online resource.
  abstract: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
  table of contents: Carbohydrate-Based Synthetic Chemistry in the Context of Drug Design -- Iminosugars: Therapeutic Applications and Synthetic Considerations -- Computational Docking as a Tool for the Rational Design of Carbohydrate-Based Drugs -- Discovery and Development of Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Dapagliflozin for the Treatment of Type 2 Diabetes -- Design, Synthesis, and Applications of Galectin Modulators in Human Health -- Discovery and Application of FimH Antagonists -- Carbohydrate-Based Anti-Virulence Compounds Against Chronic Pseudomonas aeruginosa Infections with a Focus on Small Molecules -- The Evolution of a Glycoconjugate Vaccine for Candida albicans.
  note: edited by Peter H. Seeberger, Christoph Rademacher.
  subject:
    topic: Chemistry
  subject:
    topic: Molecular biology
  subject:
    topic: Carbohydrates
  subject:
    topic: Medicinal chemistry
  subject:
    topic: Chemistry
  subject:
    topic: Medicinal Chemistry
  subject:
    topic: Carbohydrate Chemistry
  subject:
    topic: Molecular Medicine
  classification: RS400-431
  classification: 615.19
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Topics in Medicinal Chemistry, 12
  identifier: 9783319086750
  identifier: http://dx.doi.org/10.1007/978-3-319-08675-0
  record info:
    record creation date: 141114
    record change date: 20151031081018.0
    record identifier: 978-3-319-08675-0