http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Hardware/Software Co-Design and Optimization for Cyberphysical Integration in Digital Microfluidic Biochips
XII, 197 p. 98 illus., 60 illus. in color. online resource.
This book describes a comprehensive framework for hardware/software co-design, optimization, and use of robust, low-cost, and cyberphysical digital microfluidic systems. Readers with a background in electronic design automation will find this book to be a valuable reference for leveraging conventional VLSI CAD techniques for emerging technologies, e.g., biochips or bioMEMS. Readers from the circuit/system design community will benefit from methods presented to extend design and testing techniques from microelectronics to mixed-technology microsystems. For readers from the microfluidics domain, this book presents a new design and development strategy for cyberphysical microfluidics-based biochips suitable for large-scale bioassay applications. • Takes a transformative, “cyberphysical” approach towards achieving closed-loop and sensor feedback-driven biochip operation under program control; • Presents a “physically-aware” system reconfiguration technique that uses sensor data at intermediate checkpoints to dynamically reconfigure biochips; • Enables readers to simplify the structure of biochips, while facilitating the “general-purpose” use of digital microfluidic biochips for a wider range of applications.
Introduction -- Error-Recovery in Cyberphysical Biochips -- Real-Time Error Recovery Using a Compact Dictionary -- Biochemistry Synthesis under Completion-Time Uncertainties in Fluidic Operations -- Optimization of On-Chip Polymerase Chain Reaction -- Pin-Count Minimization for Application-Independent Chips -- Pro-Limited Cyberphysical Microfluidic Biochip -- Conclusions.
by Yan Luo, Krishnendu Chakrabarty, Tsung-Yi Ho.