rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: IgE Antibodies: Generation and Function
  name:
    name part: Lafaille, Juan J.
    role:
      role term: editor.
  name:
    name part: Curotto de Lafaille, Maria A.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2015
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: IX, 152 p. 21 illus., 16 illus. in color. online resource.
  abstract: This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.
  table of contents: Biology of IgE Production: IgE Cell Differentiation and the Memory of IgE Responses -- Molecular Mechanisms of IgE Class Switch Recombination -- Anti-IgE Therapy: Clinical Utility and Mechanistic Insights -- New Insights on the Signaling and Function of the High Affinity Receptor for IgE -- Helminth-Induced IgE and Protection Against Allergic Disorders -- IgE Immunotherapy Against Cancer.
  note: edited by Juan J. Lafaille, Maria A. Curotto de Lafaille.
  subject:
    topic: Medicine
  subject:
    topic: Antibodies
  subject:
    topic: Molecular biology
  subject:
    topic: Parasitology
  subject:
    topic: Allergy
  subject:
    topic: Biomedicine
  subject:
    topic: Antibodies
  subject:
    topic: Molecular Medicine
  subject:
    topic: Allergology
  subject:
    topic: Parasitology
  classification: QR186.7-186.85
  classification: 616.0798
  classification: 571.967
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Current Topics in Microbiology and Immunology, 388
  identifier: 9783319137254
  identifier: http://dx.doi.org/10.1007/978-3-319-13725-4
  record info:
    record creation date: 150102
    record change date: 20151204145916.0
    record identifier: 978-3-319-13725-4