rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances
  name:
    name part: DeWitt, Jamie C.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2015
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIII, 495 p. 49 illus., 15 illus. in color. online resource.
  abstract: This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage, and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provides critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors, and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.
  table of contents: Perfluorinated compounds: An overview -- Analysis of PFASs in biological tissues and fluids -- PFASs in the general population -- PFAS Biomonitoring in Higher Exposed Populations -- Perfluorinated Alkyl Acids in Wildlife -- Metabolism and Pharmacokinetics -- Metabolic EffectsPFAS -- Developmental Toxicity -- Neurotoxicity -- Immunotoxicity of Perfluoroalkylated Compounds -- Effects of PFOA on Endocrine-related Systems -- Carcinogenicity of Perfluoroalkyl Compounds -- Epidemiological Findings -- Dosimetric Anchoring of Toxicological Studies -- Human Health Risk Assessment of Perfluoroalkyl Acids -- Systematic Review, An Illustration of Increased Transparency in a Framework for Evaluating Immunotoxicity Associated with PFOA and PFOS Exposure -- Toxicology data for alternative “short-chain” fluorinated substances -- Conclusions and recommendations. .
  note: edited by Jamie C. DeWitt.
  subject:
    topic: Medicine
  subject:
    topic: Pharmacology
  subject:
    topic: Environmental health
  subject:
    topic: Ecotoxicology
  subject:
    topic: Biomedicine
  subject:
    topic: Pharmacology/Toxicology
  subject:
    topic: Environmental Health
  subject:
    topic: Ecotoxicology
  classification: RM1-950
  classification: 615
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Molecular and Integrative Toxicology
  identifier: 9783319155180
  identifier: http://dx.doi.org/10.1007/978-3-319-15518-0
  record info:
    record creation date: 150414
    record change date: 20151204163755.0
    record identifier: 978-3-319-15518-0