rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Stem Cell Biology in Neoplasms of the Central Nervous System
  name:
    name part: Ehtesham, Moneeb.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2015
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIII, 190 p. 16 illus., 15 illus. in color. online resource.
  abstract: This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control.
  table of contents: Regulation of Subventricular Zone-Derived Cells Migration in the Adult Brain -- The SVC and Its Relationship to Stem Cell Based Neuro-oncogenesis. - Isolation and characterization of stem cells for human central nervous system malignancies. - The role of stem cells in pediatric central nervous system malignancies. - Laboratory models for central nervous system tumor stem cell research. - Radiation Therapy for Glioma Stem Cells -- Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma -- Immunobiology and Immunotherapeutic targeting of glioma stem cells -- Emerging strategies for the treatment of tumor stem cells in central nervous system malignancies.
  note: edited by Moneeb Ehtesham.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Neurosciences
  subject:
    topic: Stem cells
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  subject:
    topic: Stem Cells
  subject:
    topic: Neurosciences
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Experimental Medicine and Biology, 853
  identifier: 9783319165370
  identifier: http://dx.doi.org/10.1007/978-3-319-16537-0
  record info:
    record creation date: 150420
    record change date: 20151030191223.0
    record identifier: 978-3-319-16537-0