rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Genomics, Personalized Medicine and Oral Disease
  name:
    name part: Sonis, DMD, DMSc, Stephen T.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2015
    edition: 1st ed. 2015.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIV, 408 p. 47 illus., 36 illus. in color. online resource.
  abstract: The objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section of the book provides basic information about genetics, genomics, and personalized medicine and the informatical methods available to apply and organize genetic data so that it has clinical relevance. Recognizing the genetic robustness of the oral cavity, the introductory section includes chapters on the oral microbiome and host genomics and response to infectious agents. The next two sections contain chapters which describe the genomics of specific oral diseases and conditions, including the genetic basis for mechanism and risk of treatment toxicities associated with cancer therapy and bisphosphonates. Four chapters focus on gene-based therapies and the pharmacogenomics applied to oral disease. The final chapter presents a provocative summary which describes a comprehensive vision of the melding of genomics to personalized medicine and the potential actionable outcomes that will likely affect clinical practice in the upcoming years.
  table of contents: Fundamentals of genetics, genomics, and personalized medicine -- Current and evolving genomic-based technologies. The oral micro biome, translational genomics and personalized medicine: the future -- Host genetics and response to Herpes simplex type I infection -- Orofacial clefts: the promise of personalized medicine for developmental anomalies -- Genetics and genomic studies of dental caries: insights into the promise of personalized medicine -- Periodontal disease -- Recurrent aphthous stomatitis puzzle in the era of the omic technologies -- Genomics and bioinformatics of oral lichen planus (OLP) -- Pemphigoid disease -- Salivary gland diseases -- Insights into oral epithelial premalignancy from the genetic/epigenetic viewpoints -- Oral cancer -- Medication-induced osteonecrosis of the jaw (MIONJ) -- Developing a gene therapy for radiation-induced dry mouth -- Radiation protection of the oral cavity/oropharynx: antioxidant strategies from MnSOD-plasmid liposomes to GS-nitroxides -- Pharmacogenomics and oral diseases -- Genetically modified Lactococcus lactis: a novel engineering system for mucosal delivery.- Personalized medicine, genomics and oral diseases: the future.
  note: edited by Stephen T. Sonis, DMD, DMSc.
  subject:
    topic: Medicine
  subject:
    topic: Human genetics
  subject:
    topic: Bioinformatics
  subject:
    topic: Biomedicine
  subject:
    topic: Human Genetics
  subject:
    topic: Bioinformatics
  classification: RB155-155.8
  classification: QH431
  classification: 611.01816
  classification: 599.935
  related item:
    title info:
      title: Springer eBooks
  identifier: 9783319179421
  identifier: http://dx.doi.org/10.1007/978-3-319-17942-1
  record info:
    record creation date: 150917
    record change date: 20150917130142.0
    record identifier: 978-3-319-17942-1