rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Stem Cells in Modeling Human Genetic Diseases
  name:
    name part: Zatz, Mayana.
    role:
      role term: editor.
  name:
    name part: Keith Okamoto, Oswaldo.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2015
    edition: 1st ed. 2015.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 147 p. 16 illus., 15 illus. in color. online resource.
  abstract: Using stem cells to investigate currently untreatable human genetic diseases is the focus of this book. Several applications of the Nobel-Prize winning, revolutionary iPS cell technology are explored in detail, including in schizophrenia, autism, Huntington’s disease, Alzheimer’s disease, spinocerebellar ataxia, medulloblastoma heterogeneity, progeria, age-related macular degeneration, and muscular dystrophy . The book is divided into seven sections, each composed of authoritative and detailed chapters. The first section provides a theoretical and practical overview of stem cells in disease modeling. The following sections divide stem cell applications into various classes of pathology- psychiatric disorders, neurodegenerative disease, neurogenesis-associated disorders, and laminopathies. Following these sections, the book discusses the future perspectives- and challenges- of iPS technology. Broad in scope and in audience, Stem Cells in Modeling Human Genetic Diseases for postgraduate students, scientists, and clinicians interested in applications of the rapidly developing field of stem cell research in disease modeling and drug development and its dynamic role within regenerative medicine.
  table of contents: Modeling Fragile X Syndrome in Human Pluripotent Cells -- Induced Pluripotent Stem Cells in Familial Dilated Cardiomyopathy.- Induced Pluripotent Stem Cells and Amyotrophic Lateral Sclerosis -- IPS Cells and Spinocerebellar Ataxia -- Induced Pluripotent Stem Cells and Vascular Disease -- iPS Cells and Cardiomyopathies -- Cancer Stem Cells and Chemoresistance -- Stem Cells in Autism Spectrum Disorders.
  note: edited by Mayana Zatz, Oswaldo Keith Okamoto.
  subject:
    topic: Life sciences
  subject:
    topic: Human genetics
  subject:
    topic: Stem cells
  subject:
    topic: Regenerative medicine
  subject:
    topic: Tissue engineering
  subject:
    topic: Life Sciences
  subject:
    topic: Stem Cells
  subject:
    topic: Regenerative Medicine/Tissue Engineering
  subject:
    topic: Human Genetics
  classification: QH588.S83
  classification: 571.6
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Stem Cell Biology and Regenerative Medicine
  identifier: 9783319183145
  identifier: http://dx.doi.org/10.1007/978-3-319-18314-5
  record info:
    record creation date: 150811
    record change date: 20151103123827.0
    record identifier: 978-3-319-18314-5