rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Electrophysiology of Unconventional Channels and Pores
  name:
    name part: Delcour, Anne H.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2015
    edition: 1st ed. 2015.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XI, 385 p. 86 illus., 38 illus. in color. online resource.
  abstract: This book is dedicated to the channels and pores that belong to an eclectic and ubiquitous class of unconventional - perhaps at times strange - pore-forming molecules, which nevertheless play fundamental roles in various organisms. These non-canonical channels may take on various and sometimes complex architectures, such as large beta-barrels or lipid-containing pores. They may originate from bacteria, viruses or intracellular organelles. For some of them, the physiologically relevant substrate may indeed be ions, and for others folded polypeptides. Some are released by cells in a soluble form that has the ability to insert into biological membranes to exert its permeabilizing effect. Many of these unconventional pores have been investigated by electrophysiology, which, by its virtue of focusing on a few or even a single unit, has provided invaluable insight into the mechanisms and structure-function relationships of these remarkable membrane entities. The chapters of this book highlight a representative set of these interesting investigations.
  table of contents: Part I Mitochondria -- Function and regulation of mitochondrial voltage-dependent anion channel -- Mitochondrial Protein Import Channels -- Electrophysiology of the mitochondrial apoptosis-induced channel, MAC -- Ceramide Channels -- Part II Bacteria and viruses -- Bacterial Porins -- Electrophysiology of Bacterial Translocons -- Viroporins -- Part III Toxins and antimicrobial peptides -- Pore-forming colicins- unusual ion channels -unusually regulated -- Anthrax Toxin Protective Antigen Forms an Unusual Channel that Unfolds and Translocates Proteins Across Membranes -- Staphylococcal b-barrel Pore-forming Toxins: Mushrooms That Breach the Greasy Barrier -- Properties of pores formed by cholesterol-dependent cytolysins and actinoporins -- Part IV Other unconventional channels -- Perforins -- Gap Junction Channels: The electrical conduit of the intercellular world -- Amyloid Peptide Channels -- From phototaxis to biomedical applications: Investigating the molecular mechanism of channelrhodopsins.
  note: edited by Anne H. Delcour.
  subject:
    topic: Life sciences
  subject:
    topic: Proteins
  subject:
    topic: Cell membranes
  subject:
    topic: Biology
    topic: Technique
  subject:
    topic: Membranes (Biology)
    topic: Mechanical properties
  subject:
    topic: Life Sciences
  subject:
    topic: Membrane Biology
  subject:
    topic: Protein Structure
  subject:
    topic: Membranes
  subject:
    topic: Biological Techniques
  classification: QH601-602
  classification: 571.64
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Springer Series in Biophysics, 18
  identifier: 9783319201498
  identifier: http://dx.doi.org/10.1007/978-3-319-20149-8
  record info:
    record creation date: 151023
    record change date: 20151030081440.0
    record identifier: 978-3-319-20149-8